Laryngomalacia No Longer An Ambiguity

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00972764
Recruitment Status : Completed
First Posted : September 7, 2009
Last Update Posted : September 7, 2009
Information provided by:
Boushahri Clinic Medical Center

Brief Summary:
The purpose of this study is to expose some of the factors that may be associated or predisposing to development of laryngomalacia.

Condition or disease

Detailed Description:
Laryngomalacia is the most common congenital malformation of the larynx and it is a self-limited disorder. It is the most common cause of stridor in newborns and infants. It results from an abnormal prolapse of supraglottic structures during inspiration. Despite its widespread prevalence, the etiology of laryngomalacia is unclear. Most infants will squeaky but otherwise well. Although affected patients do not exhibit much in the way of other physical symptoms, the unusual voice is worrisome to their parents.

Study Type : Observational
Actual Enrollment : 1500 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Laryngomalacia No Longer An Ambiguity
Study Start Date : January 2006
Actual Primary Completion Date : July 2008
Actual Study Completion Date : September 2008

Resource links provided by the National Library of Medicine

Laryngomalacia Cases

Information from the National Library of Medicine

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Ages Eligible for Study:   up to 2 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Primary care clinics

Inclusion Criteria:

  • Babies delivered with laryngomalacia with ≥ 37 weeks of gestation
  • Delivered with birth weights ≥ 2.5 kg
  • No history of natal or post-natal complications
  • From the same community

Exclusion Criteria:

  • Pre-term babies
  • History of natal or post-natal complications

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00972764

Boushahri Clinic Medical Center
Kuwait, P.O.Box :698 Salmiya, Kuwait, 22007
Sponsors and Collaborators
Boushahri Clinic Medical Center
Principal Investigator: Mohamed S EL-Sayed, MBBCh,MSc,MD New Children's Hospital, Cairo University

Responsible Party: Medical Director, Mohamed Said EL-Sayed Identifier: NCT00972764     History of Changes
Other Study ID Numbers: 461956 (BoushahriCMC)
First Posted: September 7, 2009    Key Record Dates
Last Update Posted: September 7, 2009
Last Verified: September 2009

Keywords provided by Boushahri Clinic Medical Center:
Factors Associated or Predisposing

Additional relevant MeSH terms:
Cartilage Diseases
Musculoskeletal Diseases
Laryngeal Diseases
Respiratory Tract Diseases
Otorhinolaryngologic Diseases
Musculoskeletal Abnormalities
Congenital Abnormalities
Connective Tissue Diseases