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Dual Endpoint Nerve Stimulation Versus Ultrasound in Infraclavicular Block for Hand Surgery

This study has been completed.
Information provided by:
University Health Network, Toronto Identifier:
First received: July 17, 2009
Last updated: August 10, 2009
Last verified: August 2009
Current best practice for performance of infraclavicular block dictates the use of a dual-endpoint nerve stimulation technique that still only results in a 79% success rate. Use of an ultrasound-guided technique has the potential to significantly improve success. A randomized, controlled study to evaluate this area remains to be performed and is required to demonstrate to anesthesiologists that an ultrasound-guided approach should supersede nerve stimulation as the technique of choice for infraclavicular block.

Condition Intervention
Hand Surgery Procedure: Ultrasound Guided Infraclavicular Nerve Block Procedure: Dual-Endpoint nerve stimulation

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: A Randomized Controlled Study Comparing Dual Endpoint Nerve Stimulation With Ultrasound-guided Infraclavicular Block for Hand Surgery.

Resource links provided by NLM:

Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:
  • To compare ultrasound-guided infraclavicular block with conventional dual-endpoint nerve stimulator guided infraclavicular block with regards to block success, ease of nerve localization, speed of onset, duration of block and complications.

Enrollment: 106
Study Start Date: January 2006
Study Completion Date: December 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Ultrasound
Ultrasound guided infraclavicular block
Procedure: Ultrasound Guided Infraclavicular Nerve Block
Use of Ultrasound to help guide needle placement and local anesthetic injection during infraclavicular nerve block.
Active Comparator: Dual Endpoint Nerve Stimulator
Nerve stimulator guided dual endpoint infraclavicular block
Procedure: Dual-Endpoint nerve stimulation
Use of dual-endpoint nerve stimulation to guide needle placement and local anesthetic injection during infraclavicular nerve block.


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients undergoing elective upper limb surgery at or below the elbow.
  • Patients aged >18 and <80 years
  • BMI<35

Exclusion Criteria:

  • Inability to read, write or speak English. (This is necessary because subjects will have to follow detailed instructions to allow testing of motor and sensory function. It is not feasible to have an interpreter present in the block room during performance of these procedures)
  • Contraindication to brachial plexus block
  • Existing neurological deficit in the area to be blocked
  • Known loco-regional malignancy or infection
  • Coagulopathy
  • Allergy to local anesthetic agents.
  • Chest or shoulder deformities
  • Severe respiratory disease
  • Healed but dislocated clavicle fracture
  Contacts and Locations
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Please refer to this study by its identifier: NCT00956683

Canada, Ontario
Colin McCartney
Toronto, Ontario, Canada, M5T 2S8
Sponsors and Collaborators
University Health Network, Toronto
  More Information

Responsible Party: Dr. Colin McCartney, University Health Network Identifier: NCT00956683     History of Changes
Other Study ID Numbers: 2004-006
Study First Received: July 17, 2009
Last Updated: August 10, 2009

Keywords provided by University Health Network, Toronto:
infraclavicular nerve block ultrasound dual endpoint stimulation processed this record on August 16, 2017