Influence of Posture and Gas Insufflation on Perioperative Lung Function
Recruitment status was Recruiting
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Influence of Posture, Anesthesia and Surgical Technique on Airway Resistance of the Upper and Lower Airway and Lung Function.|
- Measurement of FEV1 (forced expiratory volume in one second) and the MEF50/MIF50 ratio [ Time Frame: 18 months ] [ Designated as safety issue: No ]
- Changes in nasal airway resistance [ Time Frame: 18 months ] [ Designated as safety issue: No ]
|Study Start Date:||April 2009|
|Estimated Study Completion Date:||February 2012|
|Estimated Primary Completion Date:||October 2011 (Final data collection date for primary outcome measure)|
head down, laparoscopic
20 patients with laparoscopic surgery (radical robotic prostatectomy) in head down position
head down, open
20 patients undergoing "open"surgery (open radical prostatectomy) in head down position.
20 patients undergoing "open" surgery in horizontal position (open hemicolectomy)
Lung function, upper and lower airway resistance measurements are performed in patients in prone horizontal or head tilted down (40°) position. Half of the patients with head down position will have surgery in laparoscopic technique (including gas insufflation to achieve a pneumoperitoneum). Measurements are performed on the day prior to surgery, on the morning of surgery, 30 - 45 minutes, 2 hours, and 24 hours after extubation.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00948571
|Contact: Harald Groeben, Prof. Dr.||##49201174 ext firstname.lastname@example.org|
|Prof. Dr. Harald Groeben||Recruiting|
|Essen, Germany, 45136|
|Contact: Harald Groeben, Prof. Dr. ##49201174 ext 31109 email@example.com|
|Principal Investigator: Harald Groeben, Prof. Dr.|
|Principal Investigator:||Harald Groeben, Prof. Dr.||Klniken Essen-Mitte|