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Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study (IceCub)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00912600
Recruitment Status : Completed
First Posted : June 3, 2009
Last Update Posted : July 26, 2012
Sponsor:
Collaborator:
Institut National de la Santé Et de la Recherche Médicale, France
Information provided by (Responsible Party):
Assistance Publique - Hôpitaux de Paris

Study Description
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Brief Summary:
Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain. In this study, we prospectively studied old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.The working hypothesis was that ICU admission was associated with a 20% decrease in six-month mortality.

Condition or disease Intervention/treatment
Patient Admission Death Activities of Daily Living Other: Intensive Care Unit admission

Detailed Description:
This was a prospective multicenter observational cohort study of elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU. To be included, subjects had to be aged at least 80 years and be diagnosed by the ED physician with one of 74 conditions potentially warranting ICU admission.Outcome studied are ICU eligibility as assessed by emergency and ICU physicians, hospital and six-month death and changes in functional status in the six month following emergency department visit.
Study Design
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Study Type : Observational
Actual Enrollment : 2643 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: A Prospective Multicenter Study Examining the Criteria That Determine ICU Admission of Patients Over 80 Who Present to an Emergency Department and Evaluating the Impact of ICU Admission on Short and Mid-term Vital and Functional Outcome
Study Start Date : November 2004
Actual Primary Completion Date : January 2006
Actual Study Completion Date : February 2009
Groups and Cohorts
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Group/Cohort Intervention/treatment
1
Elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU
 Other: Intensive Care Unit admission
Intensive Care Unit admission


Outcome Measures
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Primary Outcome Measures :
  1. ICU eligibility as assessed by emergency and ICU physicians [ Time Frame: At the admission ]

Secondary Outcome Measures :
  1. Hospital death [ Time Frame: During the hospitalisation ]
  2. Change in functional status [ Time Frame: During 6 months ]
  3. Six-month death [ Time Frame: During 6 months after the end of the hospitalisation ]

Eligibility Criteria
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Ages Eligible for Study:   80 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.
Criteria

Inclusion Criteria:

  • Age over 80
  • Be assigned by the emergency physician with one of 74 conditions potentially warranting ICU admission

Exclusion Criteria:

  • Patient's refusal
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00912600


Locations
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France
Hôpital Saint-Antoine
Paris, France, 75012
Sponsors and Collaborators
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France
Investigators
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Principal Investigator: Bertrand GUIDET, MD Assistance Publique - Hôpitaux de Paris
More Information
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Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Assistance Publique - Hôpitaux de Paris
ClinicalTrials.gov Identifier: NCT00912600    
Other Study ID Numbers: AOR 03 035
First Posted: June 3, 2009    Key Record Dates
Last Update Posted: July 26, 2012
Last Verified: May 2009
Keywords provided by Assistance Publique - Hôpitaux de Paris:
Intensive Care Units
Triage
Aged, 80 and over
Death
 Activities of Daily Living
Health Services Research
Health Care Quality, Access, and Evaluation
Additional relevant MeSH terms:
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Death
Pathologic Processes