Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System

This study has been completed.
Sponsor:
Collaborator:
Ben-Gurion University of the Negev
Information provided by (Responsible Party):
Moshe Isserles, Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00912522
First received: June 2, 2009
Last updated: April 20, 2015
Last verified: April 2015
  Purpose

The investigators intend to study the role of the cortex in high- level cognition processes and sensory adaptation, by the use of non-invasive Transcranial Magnetic stimulation and various cognitive tests.


Condition Intervention Phase
Healthy Volunteers
Device: TMS
Phase 0

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Magnetic Prefrontal Stimulation for Studying the Role of the Cortex in High-level Cognition Processes and Reward System

Further study details as provided by Hadassah Medical Organization:

Primary Outcome Measures:
  • Changes in scoring of different tests and questionnaires [ Time Frame: One year ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Correlation of different tests and questionnaires [ Time Frame: One year ] [ Designated as safety issue: No ]

Enrollment: 91
Study Start Date: June 2009
Study Completion Date: June 2014
Primary Completion Date: June 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: LT PFC HIGH FREQ TMS Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: LT PFC LOW FREQ TMS Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: RT PFC HIGH FREQ TMS Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Active Comparator: RT PFC LOW FREQ TMS Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION
Sham Comparator: SHAM STIMULATION Device: TMS
TRANSCRANIAL MAGNETIC STIMULATION

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy men and women, age of 18-60
  • answered negatively to questions of TMS safety questionnaire
  • signed and declared about their agreement to participate in the study
  • hebrew speaker

Exclusion Criteria:

  • self history of significant mental disorder
  • self history or first-degree relatives history of epilepsy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00912522

Locations
Israel
Hadassah medical org
Jerusalem, Israel
Sponsors and Collaborators
Hadassah Medical Organization
Ben-Gurion University of the Negev
Investigators
Principal Investigator: Moshe Isserles, Dr. Hadassa Medical Organization
  More Information

No publications provided

Responsible Party: Moshe Isserles, MD, Hadassah Medical Organization
ClinicalTrials.gov Identifier: NCT00912522     History of Changes
Other Study ID Numbers: 0116-09-HMO-CTIL
Study First Received: June 2, 2009
Last Updated: April 20, 2015
Health Authority: Israel: Ministry of Health

Keywords provided by Hadassah Medical Organization:
reward
TMS
cognition
Motivation
Perception
Decision making

ClinicalTrials.gov processed this record on May 29, 2015