Working Memory Training in Young ADHD Children

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ClinicalTrials.gov Identifier: NCT00819611

Recruitment Status : Completed

First Posted : January 9, 2009

Last Update Posted : January 10, 2014

Sponsor:

Collaborator:

Netherlands Organisation for Scientific Research

Information provided by (Responsible Party):

Dorine Slaats, Radboud University

Study Description

Brief Summary:

The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.

Condition or disease	Intervention/treatment	Phase
Attention Deficit Disorder With Hyperactivity	Behavioral: Cogmed Working memory training Behavioral: Control version of Cogmed working memory training	Phase 4

Study Design


Study Type :	Interventional (Clinical Trial)
Actual Enrollment :	51 participants
Allocation:	Randomized
Intervention Model:	Parallel Assignment
Masking:	Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose:	Treatment
Official Title:	Working Memory Training: A Randomised Controlled Treatment Study in Young ADHD Children
Study Start Date :	June 2009
Actual Primary Completion Date :	May 2013
Actual Study Completion Date :	December 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Attention Deficit Hyperactivity Disorder Memory

U.S. FDA Resources

Arms and Interventions

Arm	Intervention/treatment
Experimental: Working memory training	Behavioral: Cogmed Working memory training 15 minutes of working memory training, 5 days a week for a period of 5 weeks
Sham Comparator: Control version of working memory training	Behavioral: Control version of Cogmed working memory training 15 minutes of 'sham' working memory training, 5 days a week for a period of 5 weeks

Outcome Measures

Primary Outcome Measures :

ADHD criteria according to the DSM-IV-TR rated by the investigator [ Time Frame: 7 weeks ]

Secondary Outcome Measures :

Neurocognitive performance and electrocortical activity [ Time Frame: 7 weeks ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:	54 Months to 88 Months (Child)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Age between 4 years/6 months and 7 years/4 months
Diagnosis ADHD, classified by the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, 2000)
A full scale IQ >= 80
Psychopharmaca- naïve or -free
Access to a PC with Windows Vista or Windows XP with internet connection and speakers at home

Exclusion Criteria:

Currently intensive (i.e. weekly) individual or group psychotherapy
Regular use of medication
Diagnosis of one or more of the following comorbid psychiatric disorders: Major depression, Bipolar disorder, Psychotic disorder, Chronically motor tic disorder or Gilles de la Tourette, Conduct disorder, any other autism spectrum disorder except for Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS), Eating disorders, Anxiety disorders
Neurological disorders (e.g. epilepsy) currently or in the past
Cardiovascular disease currently or in the past
Serious motor or perceptual handicap
Participation in another clinical trial simultaneously
Educational level and/ or socio-economic situation that makes it unlikely for the family to fulfil this study

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00819611

Locations


Netherlands
Karakter University Centre for Child and Adolescent Psychiatry Nijmegen
Nijmegen, Netherlands, 6525 GC

Sponsors and Collaborators

Radboud University

Netherlands Organisation for Scientific Research

Investigators


Principal Investigator:	Dorine Slaats-Willemse, PhD	Karakter University Centre for Child and Adolescent Psychiatry, Nijmegen

More Information

Publications:

Klingberg T, Fernell E, Olesen PJ, Johnson M, Gustafsson P, Dahlström K, Gillberg CG, Forssberg H, Westerberg H. Computerized training of working memory in children with ADHD--a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry. 2005 Feb;44(2):177-86.

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

van Dongen-Boomsma M, Vollebregt MA, Buitelaar JK, Slaats-Willemse D. Working memory training in young children with ADHD: a randomized placebo-controlled trial. J Child Psychol Psychiatry. 2014 Aug;55(8):886-96. doi: 10.1111/jcpp.12218. Epub 2014 Mar 15.


Responsible Party:	Dorine Slaats, PhD, Radboud University
ClinicalTrials.gov Identifier:	NCT00819611 History of Changes
Other Study ID Numbers:	WM01022009 RN000142
First Posted:	January 9, 2009 Key Record Dates
Last Update Posted:	January 10, 2014
Last Verified:	January 2014

Keywords provided by Dorine Slaats, Radboud University:


Attention deficit disorder with hyperactivity Working memory training Placebo	Behavioral symptoms Neuropsychology Electropsychophysiology

Additional relevant MeSH terms:


Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders	Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms

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