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Working Memory Training in Young ADHD Children

This study has been completed.
Netherlands Organisation for Scientific Research
Information provided by (Responsible Party):
Dorine Slaats, Radboud University Identifier:
First received: January 8, 2009
Last updated: January 9, 2014
Last verified: January 2014
The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.

Condition Intervention Phase
Attention Deficit Disorder With Hyperactivity
Behavioral: Cogmed Working memory training
Behavioral: Control version of Cogmed working memory training
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Working Memory Training: A Randomised Controlled Treatment Study in Young ADHD Children

Resource links provided by NLM:

Further study details as provided by Radboud University:

Primary Outcome Measures:
  • ADHD criteria according to the DSM-IV-TR rated by the investigator [ Time Frame: 7 weeks ]

Secondary Outcome Measures:
  • Neurocognitive performance and electrocortical activity [ Time Frame: 7 weeks ]

Enrollment: 51
Study Start Date: June 2009
Study Completion Date: December 2013
Primary Completion Date: May 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Working memory training Behavioral: Cogmed Working memory training
15 minutes of working memory training, 5 days a week for a period of 5 weeks
Sham Comparator: Control version of working memory training Behavioral: Control version of Cogmed working memory training
15 minutes of 'sham' working memory training, 5 days a week for a period of 5 weeks


Ages Eligible for Study:   54 Months to 88 Months   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age between 4 years/6 months and 7 years/4 months
  • Diagnosis ADHD, classified by the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, 2000)
  • A full scale IQ >= 80
  • Psychopharmaca- naïve or -free
  • Access to a PC with Windows Vista or Windows XP with internet connection and speakers at home

Exclusion Criteria:

  • Currently intensive (i.e. weekly) individual or group psychotherapy
  • Regular use of medication
  • Diagnosis of one or more of the following comorbid psychiatric disorders: Major depression, Bipolar disorder, Psychotic disorder, Chronically motor tic disorder or Gilles de la Tourette, Conduct disorder, any other autism spectrum disorder except for Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS), Eating disorders, Anxiety disorders
  • Neurological disorders (e.g. epilepsy) currently or in the past
  • Cardiovascular disease currently or in the past
  • Serious motor or perceptual handicap
  • Participation in another clinical trial simultaneously
  • Educational level and/ or socio-economic situation that makes it unlikely for the family to fulfil this study
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Please refer to this study by its identifier: NCT00819611

Karakter University Centre for Child and Adolescent Psychiatry Nijmegen
Nijmegen, Netherlands, 6525 GC
Sponsors and Collaborators
Radboud University
Netherlands Organisation for Scientific Research
Principal Investigator: Dorine Slaats-Willemse, PhD Karakter University Centre for Child and Adolescent Psychiatry, Nijmegen
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Dorine Slaats, PhD, Radboud University Identifier: NCT00819611     History of Changes
Other Study ID Numbers: WM01022009
Study First Received: January 8, 2009
Last Updated: January 9, 2014

Keywords provided by Radboud University:
Attention deficit disorder with hyperactivity
Working memory training
Behavioral symptoms

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders
Mental Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on May 25, 2017