Refinement and Assessment of New Magnetic Resonance Imaging (MRI) Technologies for Neurological Exams

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2015 by University of Michigan
General Electric
Philips Medical Systems
Information provided by (Responsible Party):
Ashok Srinivasan, M.D., University of Michigan Identifier:
First received: August 20, 2008
Last updated: December 7, 2015
Last verified: December 2015
This study is being done to assess new Magnetic Resonance Imaging (MRI) technologies such as new hardware or software designed to improve MRI examinations of the brain, spine, and head & neck regions. Software and hardware are always being improved, new machines replace old machines, software is updated and improved as well as devices used to produce better MRI images.

Condition Intervention
Nervous System Diseases
Procedure: MRI

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic

Further study details as provided by University of Michigan:

Primary Outcome Measures:
  • Improvement in quality of MRI studies in Neuroradiology [ Time Frame: 1 year ] [ Designated as safety issue: No ]

    Specific Measurement Are:

    1. Scan speed - is the new method as fast or faster than regular method(s)
    2. Signal to noise - Subjectively, or quantitatively do we get the same, better, or new contrast compared to the regular methods(s).
    3. Image contrast - Subjectively, or quantitatively do we get the same or better resolution compared to the regular method(s).
    4. Spatial resolution - Subjectively, or quantitatively do we get the same or better resolution compared to the regular method(s).
    5. Artifact - Subjectively, or quantitatively do we get the better artifact reduction compared to the regular method(s).
    6. Ergonomics - Is the new software easier to work or offer more information more cleanly than the regular software
    7. Patient comfort - Subjectively, does the new software and/or hardware make the patient's MRI experience more comfortable.

Estimated Enrollment: 500
Study Start Date: October 2004
Estimated Study Completion Date: August 2016
Estimated Primary Completion Date: May 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
NEW technology MRI
Procedure: MRI
Neurological MRI with new technology evaluation


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • If you are a male or a non-pregnant female patient
  • Normal volunteer
  • presenting to MRI for a clinically-ordered neurological or head and neck MRI exam

Exclusion Criteria:

  • Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.
  • Pregnant patients or patients who are lactating.
  • A patient who is claustrophobic
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00739518

Contact: Ashok Srivinasan, MD 734 936-88254

United States, Michigan
University of Michigan Health System Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Ashok Srivinasan, MD    734-936-8865   
Sponsors and Collaborators
University of Michigan
General Electric
Philips Medical Systems
  More Information

Responsible Party: Ashok Srinivasan, M.D., Principal Investigator, University of Michigan Identifier: NCT00739518     History of Changes
Other Study ID Numbers: HUM00041731 
Study First Received: August 20, 2008
Last Updated: December 7, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by University of Michigan:

Additional relevant MeSH terms:
Nervous System Diseases processed this record on May 24, 2016