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Association of Thyroid Autoimmunity and Chronic Urticaria

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00737451
Recruitment Status : Completed
First Posted : August 19, 2008
Last Update Posted : March 27, 2012
Information provided by (Responsible Party):

Study Description
Brief Summary:
Increase prevalence of thyroid autoimmunity is found in patients with chronic urticaria. About 5-34% of chronic urticaria patients is associated with the presence of thyroid autoimmunity who are euthyroid status whereas 5-10% of them with either hyperthyroidism or hypothyroidism.

Condition or disease Intervention/treatment
Skin Itching Chronic Urticaria Behavioral: blood sampling

Detailed Description:
There is no such report on the association of thyroid autoantibodies and chronic urticaria in Taiwan population yet. This study is designed to investigate the prevalence of thyroid autoimmunity associated with chronic urticaria in Taiwanese population. In addition, we intend to find out the change in the level of thyroid autoimmunity after the treatment in order to further understand their relationship. We also intend to find out the prognostic parameters in patients with the presence of thyroid autoimmunity and chronic urticaria.

Study Design

Study Type : Observational
Actual Enrollment : 155 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Association of Thyroid Autoimmunity and Chronic Urticaria in Taiwan
Study Start Date : March 2008
Primary Completion Date : November 2010
Study Completion Date : November 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort Intervention/treatment
skin itching Behavioral: blood sampling
blood sampling 10ml from the study subjects

Outcome Measures

Primary Outcome Measures :
  1. The prevalence of thyroid autoimmunity in chronic urticaria in Taiwan [ Time Frame: one year ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients aged 18 and above with complaint of skin itching

Inclusion Criteria:

  • 18 years old and above
  • skin itching for more than 6 months

Exclusion Criteria:

  • pure physical urticaria, infectious diseases, and food or food addictive hypersensitivity, chronic infection
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00737451

Far Eastern Memorial Hospital
Pan-Chiao, Taipei, Taiwan, 22060
Sponsors and Collaborators
Far Eastern Memorial Hospital
Principal Investigator: Jiang Ju Ying, MD Far Eastern Memorial Hospital
More Information

Responsible Party: Ju-Ying Jiang, Attending physician, Far Eastern Memorial Hospital
ClinicalTrials.gov Identifier: NCT00737451     History of Changes
Other Study ID Numbers: 96051
First Posted: August 19, 2008    Key Record Dates
Last Update Posted: March 27, 2012
Last Verified: September 2009

Keywords provided by Ju-Ying Jiang, Far Eastern Memorial Hospital:

Additional relevant MeSH terms:
Autoimmune Diseases
Skin Diseases, Vascular
Skin Diseases
Hypersensitivity, Immediate
Immune System Diseases