Emergency Department CT Scanning for Appendicitis
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ClinicalTrials.gov Identifier: NCT00734825 |
Recruitment Status
:
Completed
First Posted
: August 14, 2008
Last Update Posted
: June 28, 2012
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Appendicitis | Other: Omnipaque | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 244 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Emergency Department CT Scanning for Appendicitis: IV Contrast vs. IV and Oral Contrast |
Study Start Date : | November 2006 |
Actual Primary Completion Date : | November 2008 |
Actual Study Completion Date : | September 2010 |
Arm | Intervention/treatment |
---|---|
Active Comparator: 1
IV contrast
|
Other: Omnipaque
oral contrast for CT scan
|
Active Comparator: 2
IV contrast and oral contrast
|
Other: Omnipaque
oral contrast for CT scan
|
- sensitivity of IV contrast alone for a computed tomography scan for the diagnosis of appendicitis in the adult Emergency Department patient. [ Time Frame: immediate reading + blinded reading within 48 hours ]
- If IV contrast alone for CT scan is sensitive for the diagnosis of appendicitis in the adult Emergency department patient [ Time Frame: immediate reading and blinded reading within 48 hours ]

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- 18 years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis
Exclusion Criteria:
- pregnant patients
- patients with known IV dye or oral contrast allergy
- patients in whom acute appendicitis is not the primary diagnosis
- patients with renal insufficiency that may have significant adverse effect from IV dye

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00734825
Principal Investigator: | Andrew Kepner, MD | WellSpan Health |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Andrew Kepner, MD / Medical Director, WellSpan Health Simulation Center, WellSpan HEalth |
ClinicalTrials.gov Identifier: | NCT00734825 History of Changes |
Other Study ID Numbers: |
0607012 |
First Posted: | August 14, 2008 Key Record Dates |
Last Update Posted: | June 28, 2012 |
Last Verified: | June 2012 |
Keywords provided by WellSpan Health:
Appendicitis IV Contrast Oral Contrast CT scan |
Additional relevant MeSH terms:
Emergencies Appendicitis Disease Attributes Pathologic Processes Intraabdominal Infections Infection |
Gastroenteritis Gastrointestinal Diseases Digestive System Diseases Cecal Diseases Intestinal Diseases |