Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams
The purpose of the study is to improve MRI examinations of the chest region that will result in an improvement in patient care.
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams|
- New MRI Technologies [ Time Frame: 3 years ] [ Designated as safety issue: No ]
Assessment of the new technologies will be quantified by a variety of performance and image quality/content measures. The appropriate set of measures will be selected based on specific features offered by each assessed technology, but will be drawn from the following quantities:
- Scan speed: Scan speed is time required to set-up and run the new technique relative to the standard method.
- Signal to noise: SNR (signal to noise ratio)is the ratio of average image intensity in target tissue relative to standard deviation of background areas (outside of body). This is a fundamental parameter used to quantify relative performance of new imaging sequences/hardware/software.
- Contrast to noise: CNR (contrast to noise)is the difference in average image intensity between two target tissues relative to noise. This is a key descriptor to quantity lesion/tissue conspicuity, thus is used to characterize relative performance of new imaging sequence/hardware/software.
|Study Start Date:||January 2009|
|Estimated Study Completion Date:||December 2015|
|Estimated Primary Completion Date:||October 2015 (Final data collection date for primary outcome measure)|
Experimental: Group 2
Subjects will have Additional sequences and/or modification to MRI sequences.
Active Comparator: Group 1
Clinically ordered MRI scan. Subjects will not have any additional sequences or modifications to their clinicalliy ordered MRI
To establish an approved mechanism to recruit patients to participate in the assessment of new MRI technologies designed to improve MRI examinations of the chest region that will result in an improvement in patient care.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00727792
|United States, Michigan|
|University of Michigan Hospital|
|Ann Arbor, Michigan, United States, 48109|
|Principal Investigator:||Jadranka Stojanovska, MD||University of Michigan|