Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Diagnostic Value of HS-CRP in Stable Angina.

This study has been completed.
Information provided by:
Shiraz University of Medical Sciences Identifier:
First received: July 18, 2008
Last updated: NA
Last verified: July 2008
History: No changes posted
The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard. The investigators concluded that HS-CRP can be used as a single predictor of coronary vessel involvement in patients with stable angina and positive ETT.

Condition Intervention
Stable Angina
Positive ETT
Procedure: coronary angiography

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Diagnostic
Official Title: Diagnostic Value of HS-CRP in Stable Angina Patients With Positive Exercise Test as Compared With Coronary Angiography.

Resource links provided by NLM:

Further study details as provided by Shiraz University of Medical Sciences:

Primary Outcome Measures:
  • significant coronary lesion

Secondary Outcome Measures:
  • severity of CAD

Enrollment: 97
Study Start Date: April 2006
Study Completion Date: August 2007
Primary Completion Date: August 2007 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
positive ETT, High HS-CRP
Procedure: coronary angiography
effect of level of HS-CRP
Active Comparator: 2
positive ETT, Low HS-CRP
Procedure: coronary angiography
effect of level of HS-CRP

Detailed Description:
the investigators included 97 patients with positive ETT and stable angina and saw that Hs-CRP is the only predictor of severity of CAD as compared with coronary angiography in stable angina patients.

Ages Eligible for Study:   43 Years to 64 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Stable angina
  • Positive ETT

Exclusion Criteria:

  • Unability to perform ETT
  • Contraindications for ETT and angiography study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00719992

Iran, Islamic Republic of
Cardiology Ward Shiraz University of Medical Sciences
Shiraz, Fars, Iran, Islamic Republic of, 51318
Sponsors and Collaborators
Shiraz University of Medical Sciences
Study Director: javad kojuri, M.D. Shiraz University of Medical Sciences
  More Information

Responsible Party: Dr Javad Kojuri, Shiraz University of medical sciences Identifier: NCT00719992     History of Changes
Other Study ID Numbers: 4543
Study First Received: July 18, 2008
Last Updated: July 18, 2008

Keywords provided by Shiraz University of Medical Sciences:
Exercise tolerance test
Coronary angiography

Additional relevant MeSH terms:
Angina Pectoris
Angina, Stable
Chest Pain
Neurologic Manifestations
Nervous System Diseases
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases
Signs and Symptoms processed this record on April 28, 2017