Assess Vitamin D Levels in Those With & Without Thyroid Cancer
The purpose of this study is to evaluate Vitamin D levels in thyroid cancer patients with active disease compared with thyroid cancer patients in remission and patients with thyroid nodules.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Relationship Between Vitamin D and Thyroid Cancer|
- Number of Persons That Are Vitamin D Deficient in the Thyroid Nodule, Thyroid Cancer in Remission, and the Active Thyroid Cancer Groups. [ Time Frame: Within 12 months of enrollment in thyroid cancer collaborative registry (TCCR) database ] [ Designated as safety issue: No ]We evaluated serum calcium,creatinine,albumin,and 25-hydroxyvitaminD(25-OH-D)in 42 thyroid nodule, 45 thyroid cancer in remission, & 24 active thyroid cancer patients. We also determined the number and percent of participants in each group that had vitamin D deficiency, defined as 25-OH-D < 30 ng/ml.
Biospecimen Retention: Samples With DNA
|Study Start Date:||March 2008|
|Study Completion Date:||June 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
Thyroid Cancer in Remission Group
Thyroid Cancer-Remission Group & use of Vitamin D
Thyroid Cancer with Active Disease Group
Thyroid Cancer-Active Group & use of Vitamin D
Thyroid nodule group (no cancer) & Vit D
Thyroid nodule group without cancer and use of Vitamin D
Thyroid cancer is the most common endocrine related malignancy, increasing in incidence in recent years. There are relatively few, well known factors, both genetic and environmental, which predispose to the development of thyroid cancer. Vitamin D deficiency has been associated with other cancers, but the association between vitamin D and thyroid cancer is unknown. We plan to do a case control, pilot study to evaluate the relationship between vitamin D levels and thyroid nodules, thyroid cancer in remission, and active thyroid cancer.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00719615
|United States, Nebraska|
|University of Nebraska Medical Center|
|Omaha, Nebraska, United States, 68198|
|Principal Investigator:||Nathan W Laney, MD||University of Nebraska Medical Center, Department of Internal Medicine, Section of DEM|