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The Strategies for Post Arrest Resuscitation and Care Network (SPARC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00683683
Recruitment Status : Completed
First Posted : May 23, 2008
Last Update Posted : May 27, 2015
Sponsor:
Collaborators:
Information provided by (Responsible Party):

Study Description
Brief Summary:

Background: One of the 2010 Impact Goals of the Emergency Cardiac Care (ECC) Committee of the American Heart Association is to double survival from cardiac arrest. Currently, approximately 60% of adults and 50% of paediatric patients that regain spontaneous circulation following cardiac arrest die before leaving the hospital. A key piece of the "chain of survival" is this fifth link; the care of patients post-arrest. Although there are several modalities recommended for post arrest care, therapeutic hypothermia is the only in-hospital therapy that has been demonstrated in randomized clinical trials to improve patient outcome after cardiac arrest. Despite the strong evidence for its efficacy and the apparent simplicity of this intervention, recent surveys show that hypothermia is delivered inconsistently, incompletely, and with undue delay in hospitals receiving resuscitated patients; only 26% of physicians and 26% of hospitals regularly institute a hypothermia protocol.

Primary Objective: To design and apply a knowledge translation program for the 2005 AHA guideline on hypothermia post cardiac arrest and enable effective implementation of hypothermia in 100% of eligible OHCA patients. The integration of two robust data collection systems, which include both pre-hospital and in-hospital indicators, will give complete process of care and clinical outcome information for all cardiac arrest patients.

Primary Endpoint: the proportion of eligible out of hospital cardiac arrest patients cooled to 32-34°C within 6 hours of ED arrival.

Study Design: This project will be implemented through an established research collaborative of 43 hospitals in southern Ontario currently participating in the Toronto site of the Resuscitation Outcomes Consortium. A stepped wedge study design will be employed, whereby the intervention will be rolled-out sequentially to the participating hospitals over a number of time periods as sites reach pre-defined benchmarks. The multifaceted KT strategy will include 1) local multidisciplinary champions in ED, ICU, and Cardiology 2) A simple protocol for application of hypothermia, tailored to local needs and policy; 3) Identification of perceived and actual barriers to knowledge use; 4) Development of an implementation tool kit and 5) Providing timely feedback on benchmarks for hypothermia and outcomes


Condition or disease Intervention/treatment
Cardiac Arrest Behavioral: Knowledge Translation

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Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 32 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Strategies for Post Arrest Resuscitation and Care Network
Study Start Date : April 2008
Primary Completion Date : December 2010
Study Completion Date : December 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Cooling
Cardiac arrest patients will be cooled to 32-34°C within 6 hours of ED arrival
Behavioral: Knowledge Translation
The multifaceted KT strategy will include 1) local multidisciplinary champions in ED, ICU, and Cardiology 2) A simple protocol for application of hypothermia, tailored to local needs and policy; 3) Identification of perceived and actual barriers to knowledge use; 4) Development of an implementation tool kit and 5) Providing timely feedback on benchmarks for hypothermia and outcomes.
Other Names:
  • Clinical Protocol;
  • Reminders;
  • Audit & Feedback;
  • Network


Outcome Measures

Primary Outcome Measures :
  1. The proportion of eligible out of hospital cardiac arrest patients cooled to 32-34°C within 6 hours of ED arrival. [ Time Frame: Within 6 hours of ED arrival. ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Hospitals participating in the ROC network

Exclusion Criteria:

  • Hospitals who do not receive out-of-hospital cardiac arrest patients
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00683683


Sponsors and Collaborators
St. Michael's Hospital, Toronto
Heart and Stroke Foundation of Canada
Laerdal Medical
Investigators
Principal Investigator: Laurie Morrison, MD, MSc Sunnybrook Health Sciences Centre
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Laurie Morrison, Director, Rescu, St. Michael's Hospital, Toronto
ClinicalTrials.gov Identifier: NCT00683683     History of Changes
Other Study ID Numbers: SPARC (Morrison 038-2008)
First Posted: May 23, 2008    Key Record Dates
Last Update Posted: May 27, 2015
Last Verified: May 2014

Keywords provided by Laurie Morrison, St. Michael's Hospital, Toronto:
cardiac arrest, hypothermia, knowledge translation

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases