Family Study of Lymphoproliferative Disorders
Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.
Leukemia, Lymphocytic, Chronic, B-Cell
Monoclonal B-Cell Lymphocytosis
|Study Design:||Observational Model: Family-Based
Time Perspective: Prospective
|Official Title:||Genetic Epidemiology of Lymphoproliferative Disorders|
- Risk of blood or lymphoma [ Time Frame: Ongoing ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
We will collect blood samples from patients and their relatives for DNA and cytogenetic studies. A one time blood draw of 50 cc will be done.
|Study Start Date:||April 2004|
|Estimated Primary Completion Date:||July 2016 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00626496
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Principal Investigator:||Susan Slager, Ph.D.||Mayo Clinic|