Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00623298
Recruitment Status : Terminated
First Posted : February 26, 2008
Last Update Posted : February 26, 2008
Information provided by:
University of Konstanz

Brief Summary:
The present study is a pragmatic trial that investigates the efficacy and usefulness of two treatment modules in a sample of Rwandan genocide orphans: Narrative Exposure Therapy (NET) versus group-Interpersonal Psychotherapy (IPT). We used a half year baseline to measure the treatment-induced changes. We hypothesized that there would be a greater reduction in posttraumatic stress symptoms in the NET- than in the IPT-group and that IPT would be superior to NET in the reduction of depression symptoms.

Condition or disease Intervention/treatment Phase
Posttraumatic Stress Disorder Depression Narrative Exposure Therapy Interpersonal Psychotherapy Behavioral: Narrative Exposure Therapy Behavioral: group IPT Other: 6 months-baseline Phase 2

Detailed Description:
The 1994 genocide of Rwanda has left countless children orphaned. 26 Rwandan orphans who fulfilled DSM-IV diagnosis of PTSD were offered participation in a controlled treatment trial. A group adaptation of Interpersonal Psychotherapy (IPT, n = 14) was compared to Narrative Exposure Therapy (NET, n = 12). Main outcome measures were symptoms of PTSD and depression assessed pre-treatment, 3 months after therapy (post-test) and 6 months after therapy (follow-up) using the CAPS, MINI and Hamilton Rating Scale. At post-test, participants in both treatment conditions showed reductions in posttraumatic stress symptoms and depression symptoms. At 6-month follow-up, NET proved to be more effective in the treatment of PTSD. Only 25% (n = 3) of NET-participants but 71% (n = 10) of the IPT-participants still fulfilled PTSD criteria at follow-up. Although there was a significant reduction in depression symptoms in both treatment groups from pre-test to follow-up, NET again proved to be more effective. This treatment-trial demonstrates that NET and group-IPT are suitable treatment modules even when most severe traumatic stress and difficult living conditions have led to chronic mental suffering.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 26 participants
Allocation: Non-Randomized
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Narrative Exposure Therapy Versus Group Interpersonal Psychotherapy -A Controlled Clinical Trial With Orphaned Survivors of the Rwandan Genocide
Study Start Date : January 2005
Actual Study Completion Date : March 2006

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: 1
Behavioral: Narrative Exposure Therapy
No Intervention: 3
6-months baseline
Other: 6 months-baseline
Experimental: 2
group IPT
Behavioral: group IPT

Primary Outcome Measures :
  1. Symptoms of posttraumatic stress disorder, symptoms of depression

Information from the National Library of Medicine

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Ages Eligible for Study:   13 Years to 29 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Rwandan orphans who have experienced the genocide, who lost at least one parent during the genocide and who were no older than 18 years during the genocide

Exclusion Criteria:

  • Mental retardation
  • Psychotic symptoms or current drug or alcohol

Responsible Party: Dr. Susanne Schaal, University of Konstanz, vivo Identifier: NCT00623298     History of Changes
Other Study ID Numbers: Fogr SOSS
First Posted: February 26, 2008    Key Record Dates
Last Update Posted: February 26, 2008
Last Verified: February 2008

Keywords provided by University of Konstanz:
Posttraumatic stress disorder
Narrative Exposure Therapy
Interpersonal Psychotherapy

Additional relevant MeSH terms:
Stress Disorders, Traumatic
Stress Disorders, Post-Traumatic
Behavioral Symptoms
Trauma and Stressor Related Disorders
Mental Disorders