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Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00609427
First Posted: February 7, 2008
Last Update Posted: June 2, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
McGill University Health Center
  Purpose
The purpose of this study is to evaluate the effects of training in memory skills vs. use of external memory aids on everyday memory functioning in older people with mild cognitive impairment.

Condition Intervention Phase
Mild Cognitive Impairment Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal) Behavioral: External memory aids training Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study

Resource links provided by NLM:


Further study details as provided by McGill University Health Center:

Primary Outcome Measures:
  • Rey Auditory Verbal Learning Test [ Time Frame: 19-20 weeks ]
  • Wechsler Memory Scale - Logical Memory [ Time Frame: 19-20 weeks ]
  • Face-name associations test [ Time Frame: 19-20 weeks ]
  • Multifactorial Memory Questionnaire - Ability subscale [ Time Frame: 19-20 weeks ]

Secondary Outcome Measures:
  • Rivermead Behavioural Memory Test [ Time Frame: 19-20 weeks ]
  • FAS test (non-memory) [ Time Frame: 19-20 weeks ]
  • Category fluency (non-memory test) [ Time Frame: 19-20 weeks ]
  • Victoria Stroop Test (non-memory test) [ Time Frame: 19-20 weeks ]
  • Digit Span (non-memory test) [ Time Frame: 19-20 weeks ]
  • Multifactorial Memory Questionnaire - Strategies and Contentment subscales [ Time Frame: 19-20 weeks ]

Estimated Enrollment: 30
Study Start Date: May 2008
Study Completion Date: May 2010
Primary Completion Date: May 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: EA
Training in external memory aids
Behavioral: External memory aids training
8 weekly group sessions of training in the use of external memory aids, administered by clinical psychologist
Experimental: MT
Mnemonic training intervention
Behavioral: MEMO programme (Inst Universitaire de Geriatrie, Montreal)
8 weekly group training sessions in mnemonic strategies, administered by clinical psychologist.
No Intervention: WL
Wait-list control

Detailed Description:
Some older people experience memory loss that is worse than other people of their age, although they are not demented. This condition is known as mild cognitive impairment (MCI). Healthy older people can learn mnemonic strategies to improve their memory abilities. Can cognitive rehabilitation help people with MCI do better on mental tasks or maintain better functioning in everyday life? This study will evaluate the effects of two different rehabilitation programmes. Patients in the memory training group will learn mental strategies aimed at improving memory. Patients in the memory compensation group will learn to use external memory aids.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Clinical diagnosis of mild cognitive impairment

Exclusion Criteria:

  • Unable to speak and understand English
  • Unable to comply with treatment program due to significant comorbid illness; OR
  • Anticipated inability to attend all study sessions
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00609427


Locations
Canada, Quebec
McGill University Health Centre
Montreal, Quebec, Canada, H3A 1A1
Sponsors and Collaborators
McGill University Health Center
Investigators
Principal Investigator: Lisa Koski, PhD Research Institute of the McGill University Health Centre
  More Information

Responsible Party: Lisa Koski, Research Institute of the McGill University Health Centre
ClinicalTrials.gov Identifier: NCT00609427     History of Changes
Other Study ID Numbers: PSY-07-015
First Submitted: January 24, 2008
First Posted: February 7, 2008
Last Update Posted: June 2, 2010
Last Verified: June 2010

Keywords provided by McGill University Health Center:
cognitive training
cognitive rehabilitation

Additional relevant MeSH terms:
Cognitive Dysfunction
Cognition Disorders
Neurocognitive Disorders
Mental Disorders