We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Water and the Gastropressor Response - Diurnal Variability

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00581373
Recruitment Status : Active, not recruiting
First Posted : December 27, 2007
Last Update Posted : March 27, 2017
Sponsor:
Information provided by (Responsible Party):
Satish R. Raj, Vanderbilt University Medical Center

Brief Summary:
We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz.

Condition or disease Intervention/treatment
Orthostatic Hypotension Other: water 16 fl oz

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 20 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Water and the Gastropressor Response - Diurnal Variability (Specific Aim 1.3)
Study Start Date : August 2007
Estimated Primary Completion Date : December 2018
Estimated Study Completion Date : December 2018

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: 1
water 16 oz
Other: water 16 fl oz
water 16 fl oz in AM and repeat in late afternoon



Primary Outcome Measures :
  1. blood pressure [ Time Frame: 1 day ]

Secondary Outcome Measures :
  1. heart rate [ Time Frame: 1 day ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • orthostatic intolerance

Exclusion Criteria:

  • pregnancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00581373


Locations
United States, Tennessee
Vanderbilt University
Nashville, Tennessee, United States, 37232
Sponsors and Collaborators
Satish R. Raj
Investigators
Principal Investigator: Satish R Raj, MD MSCI Vanderbilt University

Additional Information:
Responsible Party: Satish R. Raj, Assistant Professor of Medicine & Pharmacology, Vanderbilt University Medical Center
ClinicalTrials.gov Identifier: NCT00581373     History of Changes
Other Study ID Numbers: 060553
Vanderbilt Discovery
First Posted: December 27, 2007    Key Record Dates
Last Update Posted: March 27, 2017
Last Verified: March 2017

Keywords provided by Satish R. Raj, Vanderbilt University Medical Center:
water
orthostatic hypotension
blood pressure

Additional relevant MeSH terms:
Hypotension
Hypotension, Orthostatic
Vascular Diseases
Cardiovascular Diseases
Orthostatic Intolerance
Primary Dysautonomias
Autonomic Nervous System Diseases
Nervous System Diseases