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Water and the Gastropressor Response - Diurnal Variability

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Satish R. Raj, Vanderbilt University Medical Center Identifier:
First received: December 22, 2007
Last updated: March 22, 2017
Last verified: March 2017
We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz.

Condition Intervention
Orthostatic Hypotension
Other: water 16 fl oz

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: No masking
Primary Purpose: Treatment
Official Title: Water and the Gastropressor Response - Diurnal Variability (Specific Aim 1.3)

Resource links provided by NLM:

Further study details as provided by Vanderbilt University Medical Center:

Primary Outcome Measures:
  • blood pressure [ Time Frame: 1 day ]

Secondary Outcome Measures:
  • heart rate [ Time Frame: 1 day ]

Estimated Enrollment: 20
Study Start Date: August 2007
Estimated Study Completion Date: December 2018
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
water 16 oz
Other: water 16 fl oz
water 16 fl oz in AM and repeat in late afternoon


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • orthostatic intolerance

Exclusion Criteria:

  • pregnancy
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Please refer to this study by its identifier: NCT00581373

United States, Tennessee
Vanderbilt University
Nashville, Tennessee, United States, 37232
Sponsors and Collaborators
Satish R. Raj
Principal Investigator: Satish R Raj, MD MSCI Vanderbilt University
  More Information

Additional Information:
Responsible Party: Satish R. Raj, Assistant Professor of Medicine & Pharmacology, Vanderbilt University Medical Center Identifier: NCT00581373     History of Changes
Other Study ID Numbers: 060553
Vanderbilt Discovery
Study First Received: December 22, 2007
Last Updated: March 22, 2017

Keywords provided by Vanderbilt University Medical Center:
orthostatic hypotension
blood pressure

Additional relevant MeSH terms:
Hypotension, Orthostatic
Vascular Diseases
Cardiovascular Diseases
Orthostatic Intolerance
Primary Dysautonomias
Autonomic Nervous System Diseases
Nervous System Diseases processed this record on May 24, 2017