Complications in Hypertension and Obesity

This study is currently recruiting participants. (see Contacts and Locations)
Verified May 2015 by Federal North-West Medical Research Centre
Information provided by (Responsible Party):
Conrady Alexandra, Federal North-West Medical Research Centre Identifier:
First received: October 31, 2007
Last updated: May 18, 2015
Last verified: May 2015

The study in aimed to investigate epidemiology of risk factors in Russian Federation its prognostic value aimed on acceptance of national specific definition of metabolic syndrome and guidelines for its management.

Metabolic Syndrome

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: National Investigation of Cardiovascular Complications in Arterial Hypertension and Obesity

Resource links provided by NLM:

Further study details as provided by Federal North-West Medical Research Centre:

Primary Outcome Measures:
  • cardiovascular complications [ Time Frame: 2007-2017 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • diabetes mellitus [ Time Frame: 2007-2017 ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Blood, urine, serum

Estimated Enrollment: 30000
Study Start Date: December 2007
Estimated Study Completion Date: January 2017
Estimated Primary Completion Date: September 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Age and sex-matched sample of subjects older 18 age


Inclusion Criteria:

  • Age older 18 years
  • Signed informed consent
  • Blood pressure more than 130 and/or 85 mm Hg
  • Waist circumference more than 80 sm in females and 94 in males and/or BMI more than 25 kg/m2
  • Dyslipidemia (elevated TG and/or decreased level of HDLP or therapy for high triglyceride level)
  • Fasting glucose more than 5,6 mmol/l

Exclusion Criteria:

  • Associated clinical conditions (stroke, TIA, MI, heart failure, renal disease, diabetes mellitus)
  • Severe concomitant diseases affecting outcome
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00552292

Contact: Alexandra O Conrady, MD, PhD +7812-70255-71
Contact: Elena I Baranova, professor 346-9082 ext +7812

Russian Federation
Almazov Federal Center of Heart, Blood and Endocrinology Recruiting
St.Petersburg, Russian Federation, 194156
Contact: Oxana P Rotari, MD    7-812-7025556   
Principal Investigator: Oxana Rotari, MD         
Sponsors and Collaborators
Federal North-West Medical Research Centre
Study Director: Eugene V Shlyakhto Federal North-West Medical Research Centre
  More Information

No publications provided

Responsible Party: Conrady Alexandra, professor, Federal North-West Medical Research Centre Identifier: NCT00552292     History of Changes
Other Study ID Numbers: 25/1
Study First Received: October 31, 2007
Last Updated: May 18, 2015
Health Authority: Russia: Ministry of Health of the Russian Federation

Keywords provided by Federal North-West Medical Research Centre:
metabolic syndrome
cardiovascular complications

Additional relevant MeSH terms:
Metabolic Syndrome X
Body Weight
Cardiovascular Diseases
Glucose Metabolism Disorders
Insulin Resistance
Lipid Metabolism Disorders
Metabolic Diseases
Nutrition Disorders
Signs and Symptoms
Vascular Diseases processed this record on July 30, 2015