Antioxidant Status During Burn Rehabilitation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00536822
Recruitment Status : Withdrawn (Study withdrawn due to hospital emphasis on funded studies.)
First Posted : September 28, 2007
Last Update Posted : June 18, 2013
Information provided by (Responsible Party):
Michele Gottschlich, Shriners Hospitals for Children

Brief Summary:
It is believed that children with a prior history of significant burn injury continue to manifest low levels of antioxidants well into their convalescence.The purpose of this study is to examine malondialdehyde (an oxidative lipid marker) and vitamins E, C and beta carotene status in reconstructive burn patients.

Condition or disease

Study Type : Observational
Actual Enrollment : 0 participants
Time Perspective: Prospective
Official Title: Prospective Assessment of Antioxidant Status of Pediatric Patients During Burn Rehabilitation
Study Start Date : June 2013
Actual Primary Completion Date : June 2013
Actual Study Completion Date : June 2013

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. serum antioxidant levels [ Time Frame: > 2 years postburn ]

Biospecimen Retention:   None Retained
No specimens.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   3 Years to 19 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pediatric burn

Inclusion Criteria:

  • Greater than 3 but less than 19 years
  • Reconstructive or followup outpatient care at least 1 year postburn
  • Initial burn size > 40%
  • Written informed consent and HIPAA authorization

Exclusion Criteria:

  • History of multivitamin or steroid use, liver disease, preburn malnutrition

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00536822

Sponsors and Collaborators
Shriners Hospitals for Children
Principal Investigator: Michele M Gottschlich Shriners Hospital for Children

Responsible Party: Michele Gottschlich, Research Scientist, Shriners Hospitals for Children Identifier: NCT00536822     History of Changes
Other Study ID Numbers: 07-06-04-01
First Posted: September 28, 2007    Key Record Dates
Last Update Posted: June 18, 2013
Last Verified: June 2013

Keywords provided by Michele Gottschlich, Shriners Hospitals for Children:

Additional relevant MeSH terms:
Wounds and Injuries
Molecular Mechanisms of Pharmacological Action
Protective Agents
Physiological Effects of Drugs