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Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

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ClinicalTrials.gov Identifier: NCT00520858
Recruitment Status : Completed
First Posted : August 27, 2007
Last Update Posted : April 22, 2008
Canadian Institutes of Health Research (CIHR)
Information provided by:
Queen's University

Brief Summary:
The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

Condition or disease Intervention/treatment
Abdominal Obesity Other: Resistance Exercise (RE) Other: Aerobic Exercise (AE) Other: Resistance and Aerobic Exercise (RAE)

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 145 participants
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women
Study Start Date : September 2003

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
No Intervention: C
Active Comparator: RE
Resistance Exercise
Other: Resistance Exercise (RE)
Active Comparator: AE
Aerobic Exercise
Other: Aerobic Exercise (AE)
Active Comparator: RAE
Resistance and Aerobic
Other: Resistance and Aerobic Exercise (RAE)

Primary Outcome Measures :
  1. Abdominal obesity [ Time Frame: 6 months ]

Secondary Outcome Measures :
  1. Insulin Resistance [ Time Frame: 6 Months ]

Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Men and women between 65 and 80 years of age.
  • Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
  • We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion Criteria:

  • Smokers and diabetics.
  • Women taking hormone replacement therapy.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00520858

Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6
Sponsors and Collaborators
Queen's University
Canadian Institutes of Health Research (CIHR)
Principal Investigator: Robert Ross Queen's University

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00520858     History of Changes
Other Study ID Numbers: Ross2002
First Posted: August 27, 2007    Key Record Dates
Last Update Posted: April 22, 2008
Last Verified: April 2008

Additional relevant MeSH terms:
Obesity, Abdominal
Nutrition Disorders
Body Weight
Signs and Symptoms