Clinicopathological and Molecular Correlation of Acrochordon in Relation to Human Papillomavirus Infection
|ClinicalTrials.gov Identifier: NCT00520078|
Recruitment Status : Unknown
Verified February 2007 by National Taiwan University Hospital.
Recruitment status was: Recruiting
First Posted : August 23, 2007
Last Update Posted : August 23, 2007
|Condition or disease|
|Acrochordon Skin Tag Soft Fibroma Human Papillomavirus HPV|
Acrochordon, also called soft fibroma, skin tag or fibroepithelial polyp, is a common cutaneous disorder characterized by a polypoid growth composed of fibroblasts in a loose collagenous stroma, sometimes with proliferation of blood vessels. They appear as soft, skin-colored or light brownish skin tumors. Three types of lesions may occur, (1) multiple small, furrowed papules, especially on the neck and in the axillae, (2) single or multiple filiform smooth growths in various locations, and (3) solitary bag-like pedunculated growth, seen most commonly on the lower trunk. Most regard them as a sign of cutaneous aging.
The presence of human papillomaviruses (HPVs), especially the mucosal types, has been demonstrated in acrochordon. Our previous experience on HPV typing of skin tags also confirms this finding. Though HPV is a ubiquitous virus, the presence of mucosal type HPV in non-mucosal sites is exceptional. This investigation is trying to correlate the clinicopathological and HPV molecular typing of acrochordons. A better understanding of acrochordon and its relation to HPV infection may improve the ability to prevent and treat.
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Clinicopathological and Molecular Correlation of Acrochordon in Relation to Human Papillomavirus Infection|
|Study Start Date :||August 2007|
|Estimated Study Completion Date :||August 2008|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00520078
|Contact: Tsen-Fang Tsai, MD||+886-2-23123456 ext firstname.lastname@example.org|
|National Taiwan University Hospital||Recruiting|
|Taipei, Taiwan, 100|
|Contact: Tsen-Fang Tsai, MD +886-2-23123456 ext 5734 email@example.com|
|Principal Investigator: Tsen-Fang Tsai, MD|
|Principal Investigator:||Tsen-Fang Tsai, MD||National Taiwan University Hospital|