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Capsaicin-Evoked Pain in Patients With CRPS

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00468390
Recruitment Status : Completed
First Posted : May 2, 2007
Last Update Posted : October 13, 2008
Information provided by:
Danish Pain Research Center

Brief Summary:
To evaluate the effect of capsaicin in patients with Complex Regional Pain Syndrome.

Condition or disease
CRPS (Complex Regional Pain Syndromes)

Detailed Description:

Primary outcome parameters: Capsaicin-induced pain and inflammation.

Secondary outcome parameters: Peripheral sensory and autonomic function.

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Study Type : Observational
Actual Enrollment : 40 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Capsaicin-Evoked Pain in Patients With Complex Regional Pain Syndrome
Study Start Date : April 2007
Actual Study Completion Date : January 2008

Resource links provided by the National Library of Medicine

Drug Information available for: Capsaicin

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Primary care clinic

Inclusion Criteria:

  • Age: 18 or older.
  • Pain in arm or hand > 3 months.
  • Diagnosed with CRPS acc. to diagnostic research criteria (Harder et al., 2005)
  • Inclusion of healthy subjects: age-, gender-, and BMI-matched.

Exclusion Criteria:

  • Other significant disease affecting the parameters measured, including cardiovascular disease.
  • Treatment with anticholinergics, sympathomimetics and parasympathomimetics, and alpha- and beta-adrenergics.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00468390

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Danish Pain Research Center, Aarhus University Hospital
Aarhus, Denmark, 8000
Sponsors and Collaborators
Danish Pain Research Center
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Study Chair: Troels S Jensen, MD, DMSc Danish Pain Research Center, Aarhus University Hospital

Layout table for additonal information Identifier: NCT00468390    
Other Study ID Numbers: Capsaicin in CRPS
First Posted: May 2, 2007    Key Record Dates
Last Update Posted: October 13, 2008
Last Verified: October 2008
Additional relevant MeSH terms:
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Complex Regional Pain Syndromes
Reflex Sympathetic Dystrophy
Pathologic Processes
Autonomic Nervous System Diseases
Nervous System Diseases
Peripheral Nervous System Diseases
Neuromuscular Diseases
Dermatologic Agents
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs