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Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

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ClinicalTrials.gov Identifier: NCT00447850
Recruitment Status : Completed
First Posted : March 15, 2007
Last Update Posted : September 21, 2009
Sponsor:
Information provided by:
Instituto Valenciano de Infertilidad, IVI VALENCIA

Brief Summary:
Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.

Condition or disease Intervention/treatment Phase
Premature Luteinization Procedure: endometrial biopsy Not Applicable

Study Type : Interventional  (Clinical Trial)
Official Title: Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization
Study Start Date : April 2007
Actual Primary Completion Date : July 2009
Actual Study Completion Date : July 2009

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Oocyte donors
  • Age between 18-35 years old
  • BMI 18-29
  • NORMOGONADOTROPHICS
  • PROGESTERONE ≥ 1.2 ng/ml on hCG day

Exclusion Criteria:

  • PolyCystic Ovarian Syndrome (PCOS)
  • Endometriosis

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00447850


Locations
Spain
Ivi Valencia
Valencia, Spain, 46015
Sponsors and Collaborators
Instituto Valenciano de Infertilidad, IVI VALENCIA
Investigators
Principal Investigator: Elena Labarta, MD Instituto Valenciano de la Infertilidad

Responsible Party: Dr. Elena Labarta, Instituto Valenciano de Infertilidad
ClinicalTrials.gov Identifier: NCT00447850     History of Changes
Other Study ID Numbers: VLC-EL-1006- 307-2
First Posted: March 15, 2007    Key Record Dates
Last Update Posted: September 21, 2009
Last Verified: September 2009

Additional relevant MeSH terms:
Premature Birth
Obstetric Labor, Premature
Obstetric Labor Complications
Pregnancy Complications