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Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Timothy Uhl, University of Kentucky
ClinicalTrials.gov Identifier:
NCT00445224
First received: March 6, 2007
Last updated: February 25, 2017
Last verified: February 2017
  Purpose
Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS, there have been few randomized clinical trials comparing isolated hip to isolated quadriceps strengthening. The purpose of this study is to determine how different exercises affect pain, strength, muscle activity, and function in female subjects with patellofemoral pain. The researchers hypothesize that females diagnosed with PFPS who initially participate in a hip strengthening program will report a greater perceived level of function, greater strength, less pain, and improved neuromuscular activity than those who participate in a progressive quadriceps strengthening intervention.

Condition Intervention
Patellofemoral Pain Syndrome Other: Hip Progressive Resistive Exercise Other: Quad Progressive Resistive Exercises

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Participant
Primary Purpose: Treatment
Official Title: Comparison of Early Hip Strengthening to Early Quadriceps Strengthening in the Treatment of Females With Patellofemoral Pain

Resource links provided by NLM:


Further study details as provided by Timothy Uhl, University of Kentucky:

Primary Outcome Measures:
  • Visual Analog Pain Scale (Describing Worst Pain Felt During the Past Week) [ Time Frame: weekly ]
    0 to 10 cm line with 0 representing no pain and 10 representing severe pain

  • Subjective Function by Lower Extremity Functional Scale Report Form [ Time Frame: Baseline, Mid-Intervention, and Post-Intervention ]
  • Visual Analog Pain Scale [ Time Frame: 8 week ]
    Visual analog pain scale at end of intervention. 0 to 10 cm line with 0 representing no pain and 10 representing severe pain


Secondary Outcome Measures:
  • Strength by Isometric Dynamometer [ Time Frame: Baseline, Mid, and Post-Intervention ]
  • Neuromuscular Activity by Surface Electromyographical Amplitude During Stair Descent [ Time Frame: Baseline, Mid and Post-Intervention ]
  • Objective Function by Step-down Task for 30 Seconds [ Time Frame: Baseline, Mid, and Post-Intervention ]
  • Hip Abduction Strength [ Time Frame: 8 week ]
    Side lying Hip Abduction maximal muscular contraction with a hand held dynamometer


Enrollment: 33
Study Start Date: January 2008
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Hip Progressive Resistive Exercises
Exercises targeting hip musculature such as hip abduction and hip external rotation that was progressed by increased resistance following typical progressive resistive exercise approach.
Other: Hip Progressive Resistive Exercise
Hip Progressive Resistance Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening hip abduction ad external rotation musculature.
Active Comparator: Quad Progressive Resistive Exercises
Exercises targeting quadriceps musculature such as quadriceps isometric setting, terminal knee extensions, and straight leg raises that was progressed by increased resistance following typical progressive resistive exercise approach..
Other: Quad Progressive Resistive Exercises
Quad Progressive Resistive Exercise program will be carried out by subjects under supervision once a week and then performed at home 2 additional times at home without supervision. Exercises focus on strengthening quadriceps musculature with straight leg raises and quadriceps isometrics.

Detailed Description:
Methods: Thirty-three females with PFPS will perform either initial hip strengthening (hip group) or initial quadriceps strengthening (quad group) for 4 weeks, prior to 4 weeks of a similar program of functional weight-bearing exercises. Self-reported pain, function, and functional strength were measured. Isometric strength was assessed for hip abductors, external rotators, and knee extensors. A mixed-model analysis of variance will be used to determine group differences over time.
  Eligibility

Ages Eligible for Study:   15 Years to 35 Years   (Child, Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • anterior or retropatellar knee pain reported during at least 2 of the following activities: ascending and descending stairs, hopping and running, squatting, kneeling, and prolonged sitting
  • insidious onset of symptoms not related to trauma
  • pain with compression of the patella
  • pain on palpation of the patellar facets

Exclusion Criteria:

  • symptoms present for less than one month
  • clinical evidence of other knee pathology
  • history of recent knee surgery within past one year
  • history of patellar dislocations or subluxations
  • current significant injury affecting other lower extremity joints
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00445224

Locations
United States, Kentucky
University of Kentucky
Lexington, Kentucky, United States, 40506
Sponsors and Collaborators
Timothy Uhl
Investigators
Study Chair: Timothy Uhl, PhD, ATC, PT University of Kentucky
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Timothy Uhl, Professor, University of Kentucky
ClinicalTrials.gov Identifier: NCT00445224     History of Changes
Other Study ID Numbers: 07-0138-F2L
Study First Received: March 6, 2007
Results First Received: January 28, 2010
Last Updated: February 25, 2017
Individual Participant Data  
Plan to Share IPD: Undecided
Plan Description: willing to share strength and patient reported outcome data at pre, mid, and post testing time points.

Keywords provided by Timothy Uhl, University of Kentucky:
Knee pain
Rehabilitation

Additional relevant MeSH terms:
Syndrome
Patellofemoral Pain Syndrome
Disease
Pathologic Processes
Joint Diseases
Musculoskeletal Diseases

ClinicalTrials.gov processed this record on June 23, 2017