Analgesic Effect of Intranasal Calcitonin on Patients With Fractured Ribs
This study, which will be conducted at the emergency room of the Sacré-Cœur hospital, requires the recruitment of 60 subjects and involves some telephone follow-up.
Calcitonin administered as an intranasal spray is already used to relieve pain caused by broken vertebrae and we seek to determine if it can be as efficient in the case of pain caused by broken ribs.This study aims at testing the hypothesis that subjects suffering from the accidental fracture of one or more ribs will get relief through the intranasal spraying of calcitonin and/or will use less opiate medication for pain relief (a combination of oxycodone chlorhydrate and acetaminophen called Percocet®).
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator)
Primary Purpose: Treatment
|Official Title:||Analgesic Effect of Intranasal Calcitonin on Patients With Fractured Ribs|
- Reduction of the pain level by 30% as measured on the visual analog scale of 0-100 mm on days 1, 3, 7, 14, 21, 28.
- and/or reduction the use of back-up medication on days 1, 3, 7, 14, 21, 28.
- Improvement in the quality of life and sleep.
|Study Start Date:||February 2007|
|Study Completion Date:||January 2008|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00444808
|Hôpital du Sacré-Coeur|
|Montréal, Quebec, Canada, H4J 1C5|
|Principal Investigator:||Raoul Daoust, MD||Centre de recherche hôpital du Sacré-Coeur de Montréal|