Autoimmunity in Retinitis Pigmentosa

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00433277
Recruitment Status : Unknown
Verified February 2007 by Semmelweis University.
Recruitment status was:  Active, not recruiting
First Posted : February 9, 2007
Last Update Posted : February 9, 2007
Information provided by:
Semmelweis University

Brief Summary:
Using local immune suppression, the trial seeks evidence for the hypothesis that autoimmunity plays a role in the pathomechanism of retinitis pigmentosa.

Condition or disease Intervention/treatment Phase
Retinitis Pigmentosa Drug: twice-daily dosage with 0.5% cyclosporine-A eyedrops Not Applicable

Study Type : Interventional  (Clinical Trial)
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Clinical diagnosis of retinitis pigmentosa

Exclusion Criteria:

  • Cataract
  • Extremely low ERG wave amplitude (less than 8% of normal)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00433277

Semmelweis University, Dept. of Ophthalmology
Budapest, Hungary, H-1085
Sponsors and Collaborators
Semmelweis University
Study Director: Zoltán Z. Nagy, M.D. Semmelweis University, Dept. of Ophthalmology Identifier: NCT00433277     History of Changes
Other Study ID Numbers: KMolnar
First Posted: February 9, 2007    Key Record Dates
Last Update Posted: February 9, 2007
Last Verified: February 2007

Additional relevant MeSH terms:
Retinitis Pigmentosa
Retinal Diseases
Eye Diseases
Eye Diseases, Hereditary
Retinal Dystrophies
Retinal Degeneration
Genetic Diseases, Inborn
Ophthalmic Solutions
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antifungal Agents
Anti-Infective Agents
Dermatologic Agents
Antirheumatic Agents
Calcineurin Inhibitors
Pharmaceutical Solutions