Effect of Hypnosis on Motor Cortex Excitability

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00416247
Recruitment Status : Completed
First Posted : December 27, 2006
Last Update Posted : August 5, 2010
Information provided by:
Rambam Health Care Campus

Brief Summary:
This study is intended to investigate neurophysiological mechanisms of hypnosis using transcranial magnetic stimulation (TMS) and assessment of motor cortex excitability in healthy volunteers under hypnosis.

Condition or disease Intervention/treatment Phase
Healthy Behavioral: Hypnosis Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Effect of Hypnosis on Motor Cortex Excitability
Study Start Date : December 2006
Actual Primary Completion Date : December 2007
Actual Study Completion Date : June 2009

Intervention Details:
  • Behavioral: Hypnosis

Primary Outcome Measures :
  1. Cortical Excitability [ Time Frame: Before and after intervention ]

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria: .

  1. Healthy volunteers aged 20 to 45 years.
  2. Hypnotisability above 14 as measured by the Tellegan absorption scale.

Exclusion Criteria:

  1. Psychiatric diagnosis in axis I or axis II;
  2. Documented history of head injury or seizure disorder;
  3. Evidence of a disorder which could affect peripheral and central conduction such as multiple sclerosis, motor neuron disease, carpal tunnel syndrome, cervical spondylosis, diabetic neuropathy.
  4. Any other contraindication to TMS as specified in the safety guidelines for rTMS (Wassermann, 1998) such as cardiac pacemakers or metallic deep brain electrodes.
  5. Chronic pharmacological treatment.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00416247

Rambam Medical Center
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
Principal Investigator: Ehud Klein, MD Rambam Health Care Campus

Responsible Party: Ehud Klein, MD, Head Department of Psychiatry, Rambam Medical Center Identifier: NCT00416247     History of Changes
Other Study ID Numbers: rambam2409_CTIL
First Posted: December 27, 2006    Key Record Dates
Last Update Posted: August 5, 2010
Last Verified: December 2006

Keywords provided by Rambam Health Care Campus:
Cortical excitability