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Effect of Hypnosis on Motor Cortex Excitability

This study has been completed.
Information provided by:
Rambam Health Care Campus Identifier:
First received: December 26, 2006
Last updated: August 4, 2010
Last verified: December 2006
This study is intended to investigate neurophysiological mechanisms of hypnosis using transcranial magnetic stimulation (TMS) and assessment of motor cortex excitability in healthy volunteers under hypnosis.

Condition Intervention
Healthy Behavioral: Hypnosis

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Effect of Hypnosis on Motor Cortex Excitability

Further study details as provided by Rambam Health Care Campus:

Primary Outcome Measures:
  • Cortical Excitability [ Time Frame: Before and after intervention ]

Enrollment: 20
Study Start Date: December 2006
Study Completion Date: June 2009
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Intervention Details:
    Behavioral: Hypnosis

Ages Eligible for Study:   20 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria: .

  1. Healthy volunteers aged 20 to 45 years.
  2. Hypnotisability above 14 as measured by the Tellegan absorption scale.

Exclusion Criteria:

  1. Psychiatric diagnosis in axis I or axis II;
  2. Documented history of head injury or seizure disorder;
  3. Evidence of a disorder which could affect peripheral and central conduction such as multiple sclerosis, motor neuron disease, carpal tunnel syndrome, cervical spondylosis, diabetic neuropathy.
  4. Any other contraindication to TMS as specified in the safety guidelines for rTMS (Wassermann, 1998) such as cardiac pacemakers or metallic deep brain electrodes.
  5. Chronic pharmacological treatment.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00416247

Rambam Medical Center
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
Principal Investigator: Ehud Klein, MD Rambam Health Care Campus
  More Information

Responsible Party: Ehud Klein, MD, Head Department of Psychiatry, Rambam Medical Center Identifier: NCT00416247     History of Changes
Other Study ID Numbers: rambam2409_CTIL
Study First Received: December 26, 2006
Last Updated: August 4, 2010

Keywords provided by Rambam Health Care Campus:
Cortical excitability processed this record on September 19, 2017