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Insulin Infusion in the Hospital Wards

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ClinicalTrials.gov Identifier: NCT00412347
Recruitment Status : Completed
First Posted : December 18, 2006
Last Update Posted : February 11, 2014
Information provided by (Responsible Party):
Guillermo Umpierrez, Emory University

Brief Summary:

Increasing evidence from clinical studies in Intensive Care Unit (ICU) settings indicates that insulin infusion can improve outcome measures for patients with hyperglycemia (high blood sugar) independent of a previous diagnosis of diabetes mellitus. This improvement in health could also apply to patients that have high blood sugars in various other non-critical care areas of the hospital as well. However, the data that shows improvement in health outcomes has been collected from wards that have a lower patient to provider and patient to nurse ratio, resulting in the ability for a much tighter control of the insulin infusion. We hypothesize that tight blood glucose control will provide the same benefits for patients in non-intensive care units settings but that these protocols may lead to a higher incidence of hypoglycemia (low blood sugar) and potentially to adverse outcomes in patients.

This study aims to determine the clinical outcome of patients treated with insulin infusion as well as the rate of hypoglycemic episodes in non-intensive areas. We will conduct a chart review of patients treated with insulin infusions in non-critical wards at Emory University Hospital during the period of 7/1/04 to 6/30/05. Medical records of all patients treated with intravenous insulin infusion protocols will be analyzed. Data on demographics, laboratory values, mortality rate, rate of hypoglycemic events, length of stay, as well as disposition at discharge will be analyzed.

Condition or disease Intervention/treatment
Hyperglycemia Drug: Insulin Drip Therapy

Study Type : Observational
Actual Enrollment : 200 participants
Time Perspective: Retrospective
Official Title: Insulin Infusion and Outcomes for Non-Critical Wards
Study Start Date : August 2006
Estimated Study Completion Date : December 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hyperglycemia
U.S. FDA Resources

Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Cohort of hospitalized adult subjects in a teaching institution.

Inclusion Criteria:

  • All subjects over 18 years of age that received intravenous insulin treatment on general medical and surgical wards at Emory University Hospital during the period of 7/1/2004 to 6/30/2005

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00412347

United States, Georgia
University Hospital
Atlanta, Georgia, United States, 30324
Sponsors and Collaborators
Emory University
Principal Investigator: Guillermo Umpierrez, MD Emory University

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Guillermo Umpierrez, Principal Investigator, Emory University
ClinicalTrials.gov Identifier: NCT00412347     History of Changes
Other Study ID Numbers: 1203-2005
1203-2005 ( Other Identifier: Other )
First Posted: December 18, 2006    Key Record Dates
Last Update Posted: February 11, 2014
Last Verified: February 2014

Keywords provided by Guillermo Umpierrez, Emory University:
insulin drip
general wards

Additional relevant MeSH terms:
Glucose Metabolism Disorders
Metabolic Diseases
Insulin, Globin Zinc
Hypoglycemic Agents
Physiological Effects of Drugs