We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov Menu

Cognitive Behavioral vs. Interpersonal Therapy (IPT) Prevention of Depression in Adolescents

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00374439
Recruitment Status : Completed
First Posted : September 11, 2006
Last Update Posted : April 10, 2017
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this study is to evaluate the efficacy of a cognitive-behavioral vs. an interpersonal therapy program for preventing depressive symptoms in adolescents.

Condition or disease Intervention/treatment
Depressive Symptoms Behavioral: Cognitive-behavioral Behavioral: Interpersonal Therapy

Detailed Description:
Hypothesis -- The cognitive-behavioral and interpersonal therapy prevention programs will be significantly better than the no-intervention control group in preventing depressive symptoms measured at post-intervention and at the 6-month follow-up. Gender differences also will be explored.

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 400 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Promoting Well-being in Teens
Actual Study Start Date : January 2004
Primary Completion Date : January 2006
Study Completion Date : April 2006
Arms and Interventions

Arm Intervention/treatment
Experimental: Cognitive-behavioral
Participants in this arm received a cognitive-behavioral program
Behavioral: Cognitive-behavioral
Cognitive-behavioral approach
Experimental: Interpersonal Therapy
Participants in this arm received a prevention program based on interpersonal therapy for depression
Behavioral: Interpersonal Therapy
Interpersonal therapy approach
No Intervention: No intervention
Participants in this arm did not receive an intervention, but complete assessments only

Outcome Measures

Primary Outcome Measures :
  1. Children's Depression Inventory [ Time Frame: 9 weeks ]
    Change in depressive symptoms from baseline to post-intervention at 9 weeks

  2. Center for Epidemiological Studies - Depression scale [ Time Frame: 9 weeks ]
    Change in depressive symptoms from baseline to post-intervention at 9 weeks

Eligibility Criteria

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   12 Years to 17 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All students in 9th grade Wellness classes who have parental consent

Exclusion Criteria:

  • Students without parental consent
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00374439

United States, Tennessee
Vanderbilt University
Nashville, Tennessee, United States, 37203-5721
Sponsors and Collaborators
Vanderbilt University
Principal Investigator: Judy Garber, PhD Vanderbilt University
More Information

Responsible Party: Judith Garber, Professor, Vanderbilt University Medical Center
ClinicalTrials.gov Identifier: NCT00374439     History of Changes
Other Study ID Numbers: Horowitz Dis
First Posted: September 11, 2006    Key Record Dates
Last Update Posted: April 10, 2017
Last Verified: April 2017

Keywords provided by Judith Garber, Vanderbilt University Medical Center:

Additional relevant MeSH terms:
Behavioral Symptoms