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Cognitive Behavioral vs. Interpersonal Therapy (IPT) Prevention of Depression in Adolescents

This study has been completed.
Information provided by (Responsible Party):
Judith Garber, Vanderbilt University Medical Center Identifier:
First received: September 8, 2006
Last updated: April 7, 2017
Last verified: April 2017
The purpose of this study is to evaluate the efficacy of a cognitive-behavioral vs. an interpersonal therapy program for preventing depressive symptoms in adolescents.

Condition Intervention
Depressive Symptoms
Behavioral: Cognitive-behavioral
Behavioral: Interpersonal Therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Outcomes Assessor
Primary Purpose: Prevention
Official Title: Promoting Well-being in Teens

Further study details as provided by Vanderbilt University:

Primary Outcome Measures:
  • Children's Depression Inventory [ Time Frame: 9 weeks ]
    Change in depressive symptoms from baseline to post-intervention at 9 weeks

  • Center for Epidemiological Studies - Depression scale [ Time Frame: 9 weeks ]
    Change in depressive symptoms from baseline to post-intervention at 9 weeks

Estimated Enrollment: 400
Actual Study Start Date: January 2004
Study Completion Date: April 2006
Primary Completion Date: January 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Cognitive-behavioral
Participants in this arm received a cognitive-behavioral program
Behavioral: Cognitive-behavioral
Cognitive-behavioral approach
Experimental: Interpersonal Therapy
Participants in this arm received a prevention program based on interpersonal therapy for depression
Behavioral: Interpersonal Therapy
Interpersonal therapy approach
No Intervention: No intervention
Participants in this arm did not receive an intervention, but complete assessments only

Detailed Description:
Hypothesis -- The cognitive-behavioral and interpersonal therapy prevention programs will be significantly better than the no-intervention control group in preventing depressive symptoms measured at post-intervention and at the 6-month follow-up. Gender differences also will be explored.

Ages Eligible for Study:   12 Years to 17 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All students in 9th grade Wellness classes who have parental consent

Exclusion Criteria:

  • Students without parental consent
  Contacts and Locations
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Please refer to this study by its identifier: NCT00374439

United States, Tennessee
Vanderbilt University
Nashville, Tennessee, United States, 37203-5721
Sponsors and Collaborators
Vanderbilt University
Principal Investigator: Judy Garber, PhD Vanderbilt University
  More Information

Responsible Party: Judith Garber, Professor, Vanderbilt University Medical Center Identifier: NCT00374439     History of Changes
Other Study ID Numbers: Horowitz Dis
Study First Received: September 8, 2006
Last Updated: April 7, 2017

Keywords provided by Vanderbilt University:

Additional relevant MeSH terms:
Behavioral Symptoms processed this record on May 24, 2017