Premature Coronary Atherosclerosis in Scleroderma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00372398
Recruitment Status : Completed
First Posted : September 6, 2006
Last Update Posted : September 16, 2010
Information provided by:
Tuen Mun Hospital

Brief Summary:
The purpose of this trial is to study the proportion of scleroderma patients who suffer from asymptomatic coronary atherosclerosis compared to healthy controls.

Condition or disease

Detailed Description:
Coronary calcium scores will be obtained from a group of patients with scleroderma and a group of controls. Comparison of the calcium scores will be made.

Study Type : Observational
Actual Enrollment : 28 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Premature Coronary Atherosclerosis in Scleroderma: A Case Control Study
Study Start Date : October 2006
Actual Primary Completion Date : July 2010
Actual Study Completion Date : July 2010

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
scleroderma patients

Inclusion Criteria:

  1. Age >= 18 years.
  2. Fulfillment of the American College of Rheumatology (ACR) criteria for the classification of scleroderma.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00372398

Hong Kong
Tuen Mun Hospital
Hong Kong, Hong Kong
Sponsors and Collaborators
Tuen Mun Hospital
Principal Investigator: CC Mok, MD FRCP Tuen Mun Hospital, Hong Kong

Responsible Party: CC Mok, Tuen Mun Hospital, Hong Kong Identifier: NCT00372398     History of Changes
Other Study ID Numbers: NTWC/CREC/429/06
First Posted: September 6, 2006    Key Record Dates
Last Update Posted: September 16, 2010
Last Verified: September 2010

Keywords provided by Tuen Mun Hospital:

Additional relevant MeSH terms:
Scleroderma, Systemic
Scleroderma, Diffuse
Scleroderma, Localized
Coronary Artery Disease
Myocardial Ischemia
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases
Connective Tissue Diseases
Skin Diseases
Coronary Disease
Heart Diseases