Atrial Fibrillation and the Risk for Neurological Complications
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|ClinicalTrials.gov Identifier: NCT00357227|
Recruitment Status : Unknown
Verified April 2007 by University Hospital Muenster.
Recruitment status was: Recruiting
First Posted : July 27, 2006
Last Update Posted : April 19, 2007
B8: Atrial fibrillation and the risk of neurological complications
Twenty-five thousand acute strokes are caused by atrial fibrillation every year. But even more frequent than symptomatic strokes are silent infarctions of the brain. Silent strokes remain undetected in most cases, but cumulate over time and progressively impair cognition. The impact of atrial fibrillation on subacute brain infarctions is not yet known. Moreover, it has not been elucidated so far how effective different therapeutic strategies in the treatment of atrial fibrillation prevent cognitive impairment. Thus, this study aims at evaluating the influence of different types of atrial fibrillation on silent strokes and the related impairment in cognitive functions. Other risk factors and cardiovascular diseases that are known to provoke the development of strokes will be assessed as well. So, it will be possible to isolate the contribution of atrial fibrillation to silent strokes and related cognitive impairment in segregation to other relevant factors. AF patients and controls will be examined twice in two years in order to evaluate the role of atrial fibrillation and differential therapeutic interventions with regard to the progression of silent strokes and cognitive impairment in a within subject-design.
|Condition or disease|
|Study Type :||Observational|
|Enrollment :||1000 participants|
|Observational Model:||Defined Population|
|Official Title:||Atrial Fibrillation and the Risk for Neurological Complications|
|Study Start Date :||January 2004|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00357227
|Contact: Stefan Knecht, Prof.||+49-251-83- ext email@example.com|
|University Hospital Münster, Dept. of Neurology||Recruiting|
|Münster, NRW, Germany, 48149|
|Principal Investigator: Stefan Knecht, Prof.|
|Principal Investigator:||Stefan Knecht, Prof.||University Hospital Münster, Department of Neurology|