The Microbiological Spectrum in Acute Dacryocystitis

This study has been completed.
Information provided by:
Singapore National Eye Centre Identifier:
First received: July 5, 2006
Last updated: May 11, 2010
Last verified: May 2010

Acute dacryocystitis in adults can be a very painful disease and may not respond well to medical therapy.

The purpose of this prospective non-randomised study is to determine the microorganisms causing acute dacryocystitis and the antibiotic sensitivities of these organisms.

The study also aims to correlate the microbiological findings to the severity of clinical manifestations and evaluate the effectiveness of our current practice of aspiration and empiric systemic antibiotic therapy in treating patients with acute dacryocystitis and hence review whether there is a need to alter current management strategy.


Study Type: Observational
Study Design: Time Perspective: Prospective

Further study details as provided by Singapore National Eye Centre:

Study Start Date: November 2003
Study Completion Date: May 2008
Primary Completion Date: May 2008 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Acute dacryocystitis patients



  • Painful localised fluctuant induration just inferior to the medial canthal tendon of less than 2 weeks duration.


  • Non-fluctuant lacrimal sac swelling
  • Uncooperative patient
  • Unwilling Patient
  Contacts and Locations
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Please refer to this study by its identifier: NCT00349297

Singapore National Eye Centre
Singapore, Singapore, 168751
Sponsors and Collaborators
Singapore National Eye Centre
Principal Investigator: Anshu Arundhati, MRCSED, MMED Singapore National Eye Centre
  More Information

No publications provided Identifier: NCT00349297     History of Changes
Other Study ID Numbers: R325/18/2003
Study First Received: July 5, 2006
Last Updated: May 11, 2010
Health Authority: Singapore: Health Sciences Authority

Additional relevant MeSH terms:
Eye Diseases
Lacrimal Apparatus Diseases processed this record on October 09, 2015