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Impact of Patient-Prosthesis-Mismatch on Coronary Flow Reserve

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00310947
First Posted: April 5, 2006
Last Update Posted: April 5, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Medtronic
Information provided by:
Johann Wolfgang Goethe University Hospital
  Purpose
Complete normalization of CFR following AVR for aortic stenosis was observed only for stentless valves. Besides the superior hemodynamic performance this might explain the excellent long term results of this valve design.

Condition
Coronary Artery Disease

Study Type: Observational
Study Design: Allocation: Random Sample
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Impact of Patient-Prosthesis-Mismatch and Aortic Valve Design on Coronary Flow Reserve Following Aortic Valve Replacement

Further study details as provided by Johann Wolfgang Goethe University Hospital:

Estimated Enrollment: 48
Study Start Date: March 2005
Estimated Study Completion Date: January 2006
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Aortic valve stenosis

Exclusion Criteria:

Coronary artery disease

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00310947


Locations
Germany
JW Goethe University Ffm
Frankfurt am Main, Hessen, Germany, 60590
Sponsors and Collaborators
Johann Wolfgang Goethe University Hospital
Medtronic
Investigators
Principal Investigator: Peter Kleine, MD,PhD JW Goethe University Ffm
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00310947     History of Changes
Other Study ID Numbers: Coronary flow reserve
First Submitted: March 31, 2006
First Posted: April 5, 2006
Last Update Posted: April 5, 2006
Last Verified: March 2003

Keywords provided by Johann Wolfgang Goethe University Hospital:
Coronary artery disease
Coronary flow reserve
Heart failure
prospective randomised

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases