Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00292123
Recruitment Status : Completed
First Posted : February 15, 2006
Last Update Posted : January 12, 2017
Information provided by:
National Institute on Drug Abuse (NIDA)

Brief Summary:
The primary goal of this study is to determine how contingency management can best be combined with standard or high doses of methadone to increase simultaneous abstinence from heroin and cocaine.

Condition or disease Intervention/treatment Phase
Opioid Dependence Cocaine Abuse Drug: Methadone Behavioral: Contingency Management Phase 1

Detailed Description:
A study of people pmaintained on Methadone using contingency management

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 200 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Triple (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Study Start Date : June 1999
Actual Primary Completion Date : June 2006
Actual Study Completion Date : August 2006

Resource links provided by the National Library of Medicine

Drug Information available for: Methadone

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Opioid dependence; cocaine use

Exclusion Criteria:

  • Medical or psychiatric conditions that would contraindicate participation in a methadone maintenance study; inability to give informed consent; inability to attend clinic seven days a week

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00292123

Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Principal Investigator: Kenzie Preston, PhD NIFA Intramural Research Program

Publications of Results:

Responsible Party: Kenzie L. Preston, Ph.D., Principal Investigator, National Institute on Drug Abuse Identifier: NCT00292123     History of Changes
Other Study ID Numbers: NIDAIRP 326
First Posted: February 15, 2006    Key Record Dates
Last Update Posted: January 12, 2017
Last Verified: December 2007

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Analgesics, Opioid
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Antitussive Agents
Respiratory System Agents