Impact of Anti-HIV Treatment on Labor Productivity and Costs in South Africa

This study has been terminated.
(Enrollment never initiated, study withdrawn.)
United States Agency for International Development (USAID)
Information provided by:
Boston University Identifier:
First received: December 27, 2005
Last updated: March 29, 2011
Last verified: March 2011
The purpose of this study is to determine the impact of anti-HIV treatment on the work attendance of employed people in South Africa. The study will enroll participants from a large manufacturing and distribution firm in South Africa.

HIV Infections

Study Type: Observational
Official Title: The Effectiveness of Antiretroviral Therapy in Reducing the Costs of HIV/AIDS

Resource links provided by NLM:

Further study details as provided by Boston University:

Estimated Enrollment: 120
Study Start Date: July 2005
Study Completion Date: July 2005
Detailed Description:

Little is known about the economic benefits of providing antiretroviral therapy (ART) for HIV infected patients in sub-Saharan Africa and other resource-limited areas. In South Africa, an increasing number of private sector firms are providing access to ART for their employees. One of the barriers to such action, however, is the lack of available information on the success of ART in restoring workers to full productivity, retaining skilled employees in the workforce, and reducing the costs of medical care and death and disability benefits. HIV infected employees on ART may be absent from work less often than untreated HIV infected employees, but more often than HIV uninfected employees. This study will collect data from an independent HIV/AIDS disease treatment program and a large private sector employer in Johannesburg, South Africa to estimate the benefits and costs for businesses to provide ART to eligible employees.

The study will combine individual-level medical outcome and treatment cost data from the treatment program with data on employee work attendance and retention in the workforce from the participating employer. The work attendance of HIV infected employees enrolled in the HIV/AIDS treatment program (index participants) who are either taking ART or receiving pre-ART care will be compared with each other and with that of HIV uninfected employees. There are no study visits associated with this study; all data will be collected from medical records maintained by the HIV/AIDS treatment program and the participants' employer. The financial costs and benefits of the treatment program for the participating company will also be estimated.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
see elig

Inclusion Criteria for All Participants:

  • Employed by participating company for at least 1 year prior to study entry

Inclusion Criteria for Index Participants:

  • Enrolled in the HIV/AIDS treatment program offered by the participating company

Exclusion Criteria for Index Participants:

  • Enrolled in the HIV/AIDS treatment program prior to 01/01/04 or after 06/30/05
  Contacts and Locations
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Please refer to this study by its identifier: NCT00270725

South Africa
Health Economics Research Office, Helen Joseph Hospital
Johannesburg, Gauteng, South Africa, 2092
Sponsors and Collaborators
Boston University
United States Agency for International Development (USAID)
Principal Investigator: Sydney B. Rosen, MPA Boston University
  More Information

Additional Information:
Responsible Party: Sydney Rosen, Boston University Identifier: NCT00270725     History of Changes
Other Study ID Numbers: RTC-BU-01 
Study First Received: December 27, 2005
Last Updated: March 29, 2011
Health Authority: United States: Institutional Review Board
South Africa: National Health Research Ethics Council

Keywords provided by Boston University:
Labor productivity
Antiretroviral therapy
South Africa processed this record on May 30, 2016