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Prevalence of Delirium in Patients Undergoing Cardiac Surgery

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2006 by University Health Network, Toronto.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00242151
First Posted: October 19, 2005
Last Update Posted: October 12, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University Health Network, Toronto
  Purpose

The objective of this study is to determine prevalence of postoperative delirium and confusion in patients undergoing cardiac surgery. This proposal is a pilot study designed to evaluate effect of cardiac surgery on prevalence of delirium and confusion.

The primary aim is to evaluate prevalence of delirium and confusion in patients undergoing cardiac surgery and to determine risk factors for this condition.

A secondary aim is to evaluate organic brain injury by early postoperative diffusion weighted magnetic resonance imaging (DW-MRI) in patients who develop delirium and confusion.

The hypothesis to be tested is that patients with postoperative delirium and confusion have high incidence of organic brain injury as detected by DW-MRI.


Condition
Heart Disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Prevalence of Delirium in Patients Undergoing Cardiac Surgery

Resource links provided by NLM:


Further study details as provided by University Health Network, Toronto:

Estimated Enrollment: 100
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • All patients undergoing cardiac surgery in our institute in 2 year period
  • Signed informed consent

Exclusion criteria:

  • Past history of transient ischemic attacks, stroke, symptomatic carotid artery disease.
  • Past history of psychiatric disorders
  • History of alcohol and drug abuse
  • History of severe kidney or liver disease (creatinine >2.5mg/dL and bilirubin > 2mg/dL)
  • Known contraindications to MRI
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00242151


Contacts
Contact: Jo A Carroll, RN 416-340-4800 ext 3243 jo.carroll@uhn.on.ca

Locations
Canada, Ontario
Toronto General Hospital, University Health Network Recruiting
Toronto, Ontario, Canada, M5G 2C4
Contact: Jo A Carroll, RN    416-340-4800 ext 3243    jo.carroll@uhn.on.ca   
Sub-Investigator: George N Djaiani, MD         
Sub-Investigator: Susan Abbey, MD         
Sub-Investigator: Jacek M Karski, MD         
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Rita Katznelson, MD Toronto General Hospital, University Health Network
  More Information

ClinicalTrials.gov Identifier: NCT00242151     History of Changes
Other Study ID Numbers: UHN REB 05-0223-AE
First Submitted: October 18, 2005
First Posted: October 19, 2005
Last Update Posted: October 12, 2006
Last Verified: September 2006

Keywords provided by University Health Network, Toronto:
Delirium, Confusion, Cardiac Surgery, Organic Brain Injury, Diffusion Weighted Magnetic Resonance Imaging (DW-MRI)

Additional relevant MeSH terms:
Heart Diseases
Delirium
Cardiovascular Diseases
Confusion
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Neurocognitive Disorders
Mental Disorders