Choline Quantification in Breast Cancer by MRS
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|ClinicalTrials.gov Identifier: NCT00201487|
Recruitment Status : Withdrawn (We chose to use an exsisting NMR pulse sequence already established and available at the hospital.)
First Posted : September 20, 2005
Last Update Posted : October 31, 2013
Choline has been found in increased concentration in breast cancer patients. Hypothesis: The choline signal as observed by MRS is sensitive to treatment, and a positive response to treatment will give a reduction in choline concentration.
The purpose of this study is to establish methods for quantification of choline in breast cancer by MRS
|Condition or disease|
- Establishment of new MRS sequence for choline quantification of choline. This sequence is choline-selective, and signals from water and lipids are suppressed simultaneously.
- Compare to different methods for choline quantification. The first method is quantification through an external phantom standard, containing a known concentration of choline. The other method is based on the utilisation of internal water signal as a reference.
Both calculations can be performed from the same MR exam. Ten patients will be included in the study.
|Study Type :||Observational|
|Actual Enrollment :||0 participants|
|Official Title:||Choline Quantification in Breast Cancer by MRS|
|Study Start Date :||November 2007|
|Primary Completion Date :||November 2007|
|Study Completion Date :||November 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00201487
|Principal Investigator:||Tone Bathen, PhD||NTNU, Faculty of medicine,|