Dose of Norepinephrine and the Concentration of L-Lactate in the Rectum and Stomach in Patients With Septic Shock.
|ClinicalTrials.gov Identifier: NCT00197886|
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : September 20, 2006
Norepinephrine is a drug used to increase blood pressure in patients with life-threatening infection. However, norepinephrine may limit the bloodflow to the gut, thereby causing relative lack of oxygen to the cells. This leads to increased formation of lactic acid.
This study examines whether increasing the dose of norepinephrine leads to higher concentrations of lactic acid in the rectum and stomach in patients with life-threatening infection.
|Condition or disease||Intervention/treatment||Phase|
|Septic Shock||Drug: Changing dose of norepinephrine and blood pressure||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||10 participants|
|Intervention Model:||Crossover Assignment|
|Study Start Date :||October 2004|
|Study Completion Date :||December 2005|
- L-lactate concentration in the rectum and stomach.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00197886
|Dept. of Intensive Care, Herlev University Hospital|
|Herlev, Denmark, 2730|
|Study Chair:||Anders Perner, MD,PhD||Dept. of Anaesthesia and Intensive Care, Herlev University Hospital, DK-2730 Herlev|