We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Long Term Outcomes of EV71 CNS Infection

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2005 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00172393
First Posted: September 15, 2005
Last Update Posted: October 4, 2006
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Taiwan University Hospital
  Purpose
Our study involved 142 children with EV71 CNS infections that included 61 (43%) with viral meningitis, 53 (37%) with severe CNS involvement including encephalitis, polio-like syndrome and encephalomyelitis, and 28 (20%) with cardiopulmonary failure after CNS involvement. These children were subjected to physical and neurological examinations 2.85 (range 1.0-7.39) years after disease onset. Those below the age of 6 years took the Denver developmental screening test, while those 4 years and over took the intelligence quotient (IQ) test.

Condition
Central Nervous System Infection

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Retrospective/Prospective
Official Title: Long Term Outcomes of EV71 Central Nervous System Infection

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 150
Study Start Date: January 2003
Estimated Study Completion Date: May 2005
  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   1 Month to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Virologically-confirmed EV71 cases with CNS involvement

Exclusion Criteria:

  • No evidence of EV71 infection
  • No evidence of CNS involvement
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00172393


Contacts
Contact: Luan-Yin Chang, MD 886-2-23123456 ext 3245 ly7077@tpts6.seed.net.tw

Locations
Taiwan
National Taiwan University Hsopital Recruiting
Taipei, Taiwan, 100
Contact: Luan-Yin Chang, MD, PhD    886-2-23123456 ext 3245    ly7077@tpts6.seed.net.tw   
Principal Investigator: Luan-Yin Chang, MD, PhD         
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Luan-Yin Chang, MD, PhD National Taiwan University Hospital
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00172393     History of Changes
Other Study ID Numbers: 9311700446
First Submitted: September 12, 2005
First Posted: September 15, 2005
Last Update Posted: October 4, 2006
Last Verified: June 2005

Keywords provided by National Taiwan University Hospital:
EV71,
CNS,
Outcome,
Neurological,
Psychiatric

Additional relevant MeSH terms:
Infection
Communicable Diseases
Central Nervous System Infections
Central Nervous System Diseases
Nervous System Diseases