The Effect of Liberal vs. Restrictive Transfusion Strategies on Rehabilitation After Hip Fracture Surgery
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00162617
Recruitment Status : Unknown
Verified September 2006 by Hvidovre University Hospital. Recruitment status was: Active, not recruiting
To examine the effect of two different transfusion regimens on rehabilitation after hip fracture surgery.
Condition or disease
Drug: Red blood cell transfusion
The effect of liberal vs restrictive transfusion regimens after hip fracture surgery is unresolved. Liberal transfusion regimens (transfusion trigger hgb. 6.25 mmol/l) leads to an increased use of blood products but may impact positively on rehabilitation outcome, a restrictive transfusion trigger (hbg. 5.0 mmol/l) saves blood products but may also impair postoperative rehabilitation and outcome. the study randomizes 120 elderly patients with hip fractures to either a restrictive or a liberal perioperative transfusion therapy and measures postoperative rehabilitation outcomes within a well defined multimodal rehabilitation regimen.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
65 Years and older (Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Primary hip fracture
capable of informed consent
able to ambulate independent of human assistance
no active heart condition defined as no AMI within 3 months, no unstable angina or present incompensation/pulmonary oedema
no regular transfusion demand or terminal disease.
postop. immobilization due to to surgical reasons
patient refusal to participate in relevant rehabilitation