Effect of Lifestyle Factors and Hormone Function on Breast Density in Healthy Hispanic Women Who Are Undergoing Mammography for Breast Cancer Screening
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|ClinicalTrials.gov Identifier: NCT00131950|
Recruitment Status : Completed
First Posted : August 19, 2005
Last Update Posted : July 10, 2013
RATIONALE: Lifestyle factors, such as physical activity, diet, and obesity, and hormone function may affect breast density. Screening tests, such as mammography, may help doctors find tumor cells early and plan better treatment for breast cancer.
PURPOSE: This clinical trial is studying the effect of lifestyle factors and hormone function on breast density in healthy Hispanic women who are undergoing mammography for breast cancer screening.
|Condition or disease||Intervention/treatment||Phase|
|Breast Cancer||Other: physiologic testing Other: study of socioeconomic and demographic variables Procedure: breast imaging study Procedure: study of high risk factors||Not Applicable|
- Correlate physical activity, diet, and obesity, as measured by body mass index and waist circumference, with percent breast density and the absolute estimate of total dense breast area in healthy Hispanic women undergoing screening mammography.
- Correlate fasting serum insulin growth factor (IGF)-1 and the molar ratio of IGF-1 to IGF binding protein-3 with breast density in participants undergoing screening mammography.
- Correlate insulin concentration and insulin resistance with breast density in participants undergoing screening mammography.
OUTLINE: This is a multicenter study.
Participants undergo blood collection and physical examination. Participants also complete breast cancer risk factor, food frequency, and physical activity questionnaires and receive breast health and physical activity education. Participants then undergo a digital screening mammogram. Participants are notified of mammogram results.
PROJECTED ACCRUAL: A total of 114 participants will be accrued for this study.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Chicago Breast Health Project, Phase II|
|Study Start Date :||August 2003|
|Actual Study Completion Date :||November 2005|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00131950
|United States, Illinois|
|Robert H. Lurie Comprehensive Cancer Center at Northwestern University|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Susan M. Gapstur||Robert H. Lurie Cancer Center|