CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis
|ClinicalTrials.gov Identifier: NCT00131001|
Recruitment Status : Unknown
Verified April 2007 by Hospices Civils de Lyon.
Recruitment status was: Active, not recruiting
First Posted : August 17, 2005
Last Update Posted : October 20, 2008
PURPOSE: The purpose of this clinical trial is to study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis.
MATERIALS AND METHODS: The diagnostic accuracies of Doppler ultrasound (DUS), contrast-enhanced magnetic resonance angiography (CEMRA) and computed tomography angiography (CTA) were compared with digital subtraction angiography (DSA) in a multicenter study (CARMEDAS; 206 patients assessable) and in a meta-analysis (for CEMRA and CTA). The direct costs of each imaging method were calculated in 2 university medical centers. Eight hypothetical models were studied with DUS considered as the first-line imaging method and either CEMRA or CTA or DSA as the second or third line method. The effectiveness criterion was the number of potential avoided strokes for each strategy and for 1000 patients.
|Condition or disease||Intervention/treatment||Phase|
|Carotid Stenosis||Procedure: contrast-enhanced magnetic resonance angiography||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||300 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis|
|Study Start Date :||April 2001|
- To study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00131001
|Hôpital Louis Pradel|
|Bron, France, 69677|
|Principal Investigator:||Philippe DOUEK, MD||Hospices Civils de Lyon|