Improved Stroke Outcome at 6 Months
|ClinicalTrials.gov Identifier: NCT00122798|
Recruitment Status : Completed
First Posted : July 22, 2005
Last Update Posted : June 27, 2006
|Condition or disease||Intervention/treatment||Phase|
|Stroke||Procedure: Stroke treatment||Phase 4|
Background/Aim of the study: To further reduce the 6 months stroke morbidity and mortality in a high volume stroke hospital and to compare the results with national and international data.
Methods: 204 consecutive stroke patients are analyzed in a prospective study in a single center teaching institution. The intervention consists of a structured therapeutic chain of 290 collaborating GPs, a standardised acute hospital proceeding overlapping with an early integrated neurovascular rehabilitation within the same institution. Primary endpoints include death and dependence at 6 months, secondary endpoints are the length of hospital stay (LOS) and the quantitative analysis of physical and psychosocial impairments. The data are directly compared with the same endpoints of the Swiss subgroup of the international stroke trial (IST) and recent international data.
Results: At 6 months, mortality is significantly lower with 12 % (compared to 23 % in the IST trial) and only 39 % (67 %) of the patients are dead or dependent. Stroke severity is similar as in other study populations. Median LOS is 15 days in the acute clinic and 39 days in the rehabilitation institution. The psychosocial outcome compares favorably to a matched control group.
Conclusions: A structured chain of acute stroke treatment overlapping with an early integrated rehabilitation is superior compared to national and international ischemic stroke trial data.
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Observational Model:||Defined Population|
|Observational Model:||Natural History|
|Official Title:||Improved Stroke Outcome at 6 Months Attained by a Chain of Structured Acute Treatment With Integrated Rehabilitation and Supported Discharge|
|Study Start Date :||January 2002|
|Estimated Study Completion Date :||January 2005|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00122798
|Baden, Aargau, Switzerland, 5404|
|Principal Investigator:||Juerg H Beer, M.D||Dept of Medicine, Kantonsspital Baden, Switzerland|