Functional Circuit Training in Older Adults With Congestive Heart Failure
|ClinicalTrials.gov Identifier: NCT00108147|
Recruitment Status : Completed
First Posted : April 15, 2005
Last Update Posted : March 6, 2009
|Condition or disease||Intervention/treatment||Phase|
|Heart Failure, Congestive||Procedure: Circuit Training Procedure: Cardiac Rehabilitation Procedure: Flexibility and toning||Not Applicable|
In older (65 years of age or older) patients with congestive heart failure, we propose to:
- Assess: a) Peak aerobic capacity (peak VO2) during a monitored, standardized treadmill test; b) Oxygen uptake kinetics and heart rate during a standardized submaximal treadmill test; c) Performance on a set of functional mobility tasks; d) Self-report of physical disability and difficulty in performing daily tasks, and physical activity.
- Conduct a 12-week randomized controlled trial, comparing changes in these assessed measures in patients randomized to three different groups: 1) standard cardiac rehabilitation using bicycle exercise; 2) group functional circuit training focusing on exercises that involve functional mobility tasks and a home-activities exercise component; 3) a chair-based, flexibility and "toning " (low level resistance) group control exercise.
- Reassess all groups after an additional 12 weeks in the measures identified above to identify how well the three groups maintain their function.
- Examine the mechanisms underlying change in functional mobility performance and self-reported function as a result of the interventions
Primary hypothesis 1: Compared to chair-based exercise controls at the end of week 12, both the cardiac rehabilitation and functional circuit training groups will show improvements in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.
Primary hypothesis 2: Compared to the other two groups that are given exercise instructions only, the functional circuit training group, who continue their home activities exercise program, show less decline by week 24 in measures of peak aerobic capacity, submaximal oxygen uptake kinetics, functional mobility performance, and self-reported function.
Secondary hypothesis: Measures of submaximal oxygen uptake kinetics are better predictors of changes in functional mobility performance and self-reported function than peak aerobic capacity, muscle strength, joint range of motion, balance, and behavioral factors (such as depression).
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Parallel Assignment|
|Official Title:||Functional Circuit Training in Older Adults With Congestive Heart Failure|
|Study Start Date :||October 2003|
Procedure: Circuit Training
Active Comparator: 2
Procedure: Cardiac Rehabilitation
Active Comparator: 3
Flexibility and toning
Procedure: Flexibility and toning
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00108147
|United States, Michigan|
|VA Ann Arbor Healthcare System|
|Ann Arbor, Michigan, United States, 48113|
|Principal Investigator:||Neil Alexander, MD||VA Ann Arbor Healthcare System|