A Medication Adherence Intervention for HIV Infected Veterans
|ClinicalTrials.gov Identifier: NCT00013065|
Recruitment Status : Completed
First Posted : March 16, 2001
Last Update Posted : April 7, 2015
|Condition or disease|
It is estimated that the VHA is caring for nearly 40 percent of all HIV-infected veterans. To benefit from recent improvements in anti-HIV therapy, patients need to take their medications consistently.
Optimizing health for HIV patients requires excellent adherence to antiretroviral medication regimens. However, its unclear how best to incorporate adherence education and support programs into VA HIV outpatient care. We implemented and evaluated a pharmacist program (ACE) and a Pager reminder program to support adherence in veterans with HIV.
We used a quasi-experimental design with pre-post evaluation at four VA Centers. Three treatment conditions (ACE, Pager, Usual Care) were rolled-in sequentially over two study phases, allowing for group comparisons between conditions. ACE is a multi-component manualized 4-session, individual patient education and support program by trained pharmacists. The Pager intervention used alphanumeric pagers to remind patients of dosing times. Electronically-monitored medication adherence (MEMS), self-report questionnaires, and pharmacy refill records were collected. Qualitative site interviews were collected before and after interventions to assist with program evaluation. Multilevel mixed models were used to analyze main study outcomes over time. Secondary analyses compared subgroup who actually received all ACE sessions (�as treated�) to controls.
Project has been completed and Final Report submitted to HSR&D CO.
|Study Type :||Observational|
|Estimated Enrollment :||210 participants|
|Official Title:||A Medication Adherence Intervention for HIV Infected Veterans|
|Actual Study Completion Date :||December 2003|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00013065
|United States, Arizona|
|Southern Arizona VA Health Care System, Tucson, AZ|
|Tucson, Arizona, United States, 85723|
|United States, California|
|VA Palo Alto Health Care System, Palo Alto, CA|
|Palo Alto, California, United States, 94304-1290|
|VA San Diego Healthcare System, San Diego, CA|
|San Diego, California, United States, 92161|
|VA Greater Los Angeles Healthcare System, West Los Angeles, CA|
|West Los Angeles, California, United States, 90073|
|Principal Investigator:||Allen L. Gifford, MD||VA San Diego Healthcare System, San Diego, CA|