Pooled Analysis of NHANES I/II--Race, Gender, and CHD

This study has been completed.
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
First received: May 25, 2000
Last updated: June 23, 2005
Last verified: March 2005

To conduct a pooled analysis of NHANES I/II data on race, gender, and coronary heart disease.

Cardiovascular Diseases
Coronary Disease
Heart Diseases

Study Type: Observational
Study Design: Observational Model: Natural History

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Study Start Date: August 1997
Estimated Study Completion Date: July 2000
Detailed Description:


Over the last 25 years, a sustained and marked decline in death rates from coronary heart disease (CHD) has occurred for all major segments of the U.S. population. Recently, however, the decline has proceeded less rapidly in blacks than in whites, and in women than men. These trends have focused further attention on possible heterogeneity in the risk factor patterns among the demographic sub-groups. Previous studies of CHD risk factors in blacks and whites using the First National Health and Examination Survey Epidemiologic Follow-up Study (NHEFS-I, 11-year follow-up), including this group's own work, demonstrate its potential strengths, while at the same time foundering on the problem of low statistical power. With the extension of the follow-up of NHANES-I cohort (1971-1974) to 1987 (14 years) and the completion of 14-year follow-up for NHANES II cohort (1976-1980), a strong rationale exists to undertake a "pooling project." The resulting data set would provide optimal characterization of CHD risk at the national level.


The study sought to determine whether data from NHANES I and NHANES II could be pooled. To accomplish this, the distribution of baseline measures was assessed and a determination was made whether the same logistic prediction equations fitted both studies. Also, gender-race differences were examined in individual exposure-outcome relationships, patterns of co-morbidity, and population attributable risks. .


Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No

No eligibility criteria

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Please refer to this study by its ClinicalTrials.gov identifier: NCT00005492

Sponsors and Collaborators
Investigator: Youlian Liao Loyola University
  More Information

ClinicalTrials.gov Identifier: NCT00005492     History of Changes
Other Study ID Numbers: 5009
Study First Received: May 25, 2000
Last Updated: June 23, 2005
Health Authority: United States: Federal Government

ClinicalTrials.gov processed this record on March 25, 2015