Markers and Mechanisms of Macrovascular Disease in IDDM

This study has been completed.
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Medical University of South Carolina Identifier:
First received: May 25, 2000
Last updated: April 13, 2015
Last verified: August 2008
To elucidate the biochemical, metabolic, and genetic markers and mechanisms of macrovascular disease in insulin dependent diabetes mellitus (IDDM).

Cardiovascular Diseases
Diabetes Mellitus
Heart Diseases
Diabetes Mellitus, Insulin-dependent

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Medical University of South Carolina:

Biospecimen Retention:   Samples Without DNA
Both DNA samples as well as plasma, serum and urine samples were collected from the DCCT/EDIC cohort.

Enrollment: 1063
Study Start Date: September 1996
Study Completion Date: August 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
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Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with type 1 diabetes enrolled in the DCCT/EDIC cohort who agreed to participate in our sub-study were enrolled
No eligibility criteria
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00005474

Sponsors and Collaborators
Medical University of South Carolina
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Maria Lopes-Virella Medical University of South Carolina
  More Information


Responsible Party: Medical University of South Carolina Identifier: NCT00005474     History of Changes
Other Study ID Numbers: 4958  P01HL055782-10 
Study First Received: May 25, 2000
Last Updated: April 13, 2015
Health Authority: United States: Federal Government

Additional relevant MeSH terms:
Cardiovascular Diseases
Diabetes Mellitus
Diabetes Mellitus, Type 1
Arterial Occlusive Diseases
Autoimmune Diseases
Endocrine System Diseases
Glucose Metabolism Disorders
Immune System Diseases
Metabolic Diseases
Vascular Diseases processed this record on May 03, 2016