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Study of Axial Mobility Exercises in Parkinson Disease

This study has been completed.
Information provided by:
Office of Rare Diseases (ORD) Identifier:
First received: February 24, 2000
Last updated: June 23, 2005
Last verified: April 1998


I. Compare the benefit of exercise versus usual care (no exercise) on impairments and functional limitations in patients with Parkinson disease.

Condition Intervention
Parkinson Disease Behavioral: Exercise

Study Type: Interventional
Study Design: Primary Purpose: Educational/Counseling/Training

Resource links provided by NLM:

Further study details as provided by Office of Rare Diseases (ORD):

Estimated Enrollment: 80
Study Start Date: May 1995
Estimated Study Completion Date: December 1997
Detailed Description:

PROTOCOL OUTLINE: This is a randomized study. Patients assigned to the Axial Mobility Exercise Program participate 3 times a week for 10 weeks. The program consists of individualized exercises specifically directed toward restoration of axial mobility in the context of functional tasks.

Patients assigned to the control group receive standard care (no exercise).


Ages Eligible for Study:   50 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No


--Disease Characteristics-- Stage 2 or 3 Parkinson disease (Hoehn/Yahr scale) Able to ambulate independently Able to function independently in home Moderate rigidity No moderate or severe tremor --Prior/Concurrent Therapy-- Concurrent stable pharmacologic regimen required --Patient Characteristics-- Cardiovascular: No unstable angina Other: No psychiatric or medical contraindication to exercise, e.g., dementia, hip fracture; no other neurologic disorder, e.g., stroke, multiple sclerosis; resides within 30 miles of Duke University

  Contacts and Locations
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Please refer to this study by its identifier: NCT00004760

Sponsors and Collaborators
Duke University
Study Chair: Margaret Schenkman Duke University
  More Information Identifier: NCT00004760     History of Changes
Other Study ID Numbers: 199/11694
Study First Received: February 24, 2000
Last Updated: June 23, 2005

Keywords provided by Office of Rare Diseases (ORD):
Parkinson disease
Neurologic and psychiatric disorders
Rare disease

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases processed this record on September 19, 2017