Must have known or suspected coronary artery calcification, including subjects of age equal to or greater than 55 years (men), or 65 years (women).
Must be at increased risk for CAD. (Chronic hypertension greater than 140/90, cholesterolemia greater than 130 mg/dl, active cigarette smoker, or diabetes mellitus.)
Must be 18 years of age or older.
Females must not be pregnant or considering pregnancy and must not be lactating.
Must not have any surgical devices which may interfere with imaging: heart valves, pacemakers, sternal wire sutures, epicardial pacer leads, metallic coronary stents.
Must not have tachycardia greater than 90 bpm at time of scanning, or other fast or irregular rhythm.
Must not be obese. Patients weighing more than 300 pounds will be excluded since this is the table weight limit for the EBCT scanner.
Must be able to suspend respiration for 28 seconds at time of scanning.
Must be able to give informed consent.