Subjects must be between the ages of 11 and 21 years.
Subjects must be diagnosed with HIV for at least one year (to ensure sufficient opportunity to experience living with a chronic condition such that adherence level is unlikely to be the result of skill or knowledge deficits).
Subjects must be prescribed oral medications (e.g., pills, liquids, inhaler) to be taken on a daily basis.
Subjects must be living with same female caregiver for at least one year.
Subjects must have a telephone number where he/she can be contacted during the two weeks after recruitment.
The adolescent and mother must be able to provide informed consent.
Adolescents must not have mental retardation or developmental delay that would prevent the adolescent from reading and comprehending the questionnaire.